Effectiveness of an outpatient rehabilitation programme in patients with neuralgic amyotrophy and scapular dyskinesia: a randomised controlled trial

被引:4
作者
Janssen, Renske M. J. [1 ]
Lustenhouwer, Renee [2 ,3 ]
Cup, Edith H. C. [2 ]
van Alfen, Nens [4 ]
Ijspeert, Jos [2 ]
Helmich, Rick C. [4 ,5 ]
Cameron, Ian G. M. [5 ]
Geurts, Alexander C. H. [2 ]
van Engelen, Baziel G. M. [4 ]
Graff, Maud J. L. [1 ]
Groothuis, Jan T. [2 ,6 ]
机构
[1] Radboud Univ Nijmegen, Radboud Inst Hlth Sci, Rehabil, Med Ctr, Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Rehabil, Nijmegen Med Ctr, Nijmegen, Netherlands
[3] Vrije Univ, Fac Sci, Ctr Neurogen & Cognit Res, Dept Funct Genom, Amsterdam, Netherlands
[4] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Neurol, Nijmegen Med Ctr, Nijmegen, Netherlands
[5] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Donders Ctr Cognit Neuroimaging, Nijmegen Med Ctr, Nijmegen, Netherlands
[6] Radboud Univ Nijmegen, Rehabil, Donders Inst Brain Cognit & Behav, NL-5500 HB Nijmegen, Netherlands
关键词
randomised trials; rehabilitation; peripheral neuropathology; neuromuscular; QUESTIONNAIRE; PAIN; EFFICACY; VALIDITY; FATIGUE;
D O I
10.1136/jnnp-2022-330296
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background Neuralgic amyotrophy (NA) is an acute inflammation of nerves within the brachial plexus territory leading to severe pain and multifocal paresis resulting in > 60% of patients having residual complaints and functional limitations correlated with scapular dyskinesia. Our primary aim was to compare the effects of multidisciplinary rehabilitation (MR), focused on motor relearning to improve scapular dyskinesia and self-management strategies for reducing pain and fatigue, with usual care (UC) on shoulder, arm and hand functional capability in patients with NA.Methods In a non-blinded randomised controlled trial (RCT), patients with NA (aged >= 18 years, scapular dyskinesia, > 8 weeks after onset) were randomised to either an MR or an UC group. MR consisted of a diagnostic multidisciplinary consultation and eight sessions of physical and occupational therapy. Primary outcome was functional capability of the shoulder, arm and hand assessed with the Shoulder Rating Questionnaire-Dutch Language Version (SRQ- DLV). Results We included 47 patients with NA; due to dropout, there were 22 participants in MR and 15 in UC for primary analysis. The mean group difference adjusted for sex, age and SRQ- DLV baseline score was 8.60 (95%CI: 0.26 to 16.94, p=0.044). The proportion attaining a minimal clinically relevant SRQ- DLV improvement (>= 12) was larger for the MR group (59%) than the UC group (33%) with a number needed to treat of 4.Conclusion This RCT shows that an MR programme focused on motor relearning to improve scapular dyskinesia, combined with self-management strategies for reducing pain and fatigue, shows more beneficial effects on shoulder, arm and hand functional capability than UC in patients with NA.
引用
收藏
页码:474 / 481
页数:8
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