Effect of vascular geometry on haemodynamic changes in a carotid artery bifurcation using numerical simulation

被引：5

作者：

Abhilash, H. N. ^{[1
]}

Yanagita, Yoshiki ^{[2
]}

Pai, Raghuvir ^{[1
]}

Zuber, Mohammad ^{[3
]}

Tamagawa, Masaaki ^{[2
]}

Prakashini, K. ^{[4
]}

Kamath, S. Ganesh ^{[5
]}

Padmakumar, R. ^{[6
]}

Barboza, A. B. V. ^{[1
]}

Rao, V. R. K. ^{[7
]}

Khader, S. M. Abdul ^{[1
,8
]}

机构：

[1] Manipal Acad Higher Educ, Manipal Inst Technol, Dept Mech & Ind Engn, Manipal 576104, India

[2] Kyushu Inst Technol, Grad Sch Life Sci & Syst Engn, Dept Biol Funct Engn, Kitakyushu, Fukuoka 8080196, Japan

[3] Manipal Acad Higher Educ, Dept Aeronaut & Automobile Engn, Manipal Inst Technol, Manipal 576104, India

[4] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Radiodiag & Imaging, Manipal 576104, Karnataka, India

[5] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Orthoped, Manipal 576104, India

[6] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Cardiol, Manipal, India

[7] Krishna Inst Med Sci, Dept Neurosurg, Secunderabad, India

[8] Manipal Inst Technol, Dept Mech & Ind Engn, Manipal 576104, India

来源：

CLINICAL NEUROLOGY AND NEUROSURGERY | 2024年 / 237卷

关键词：

Carotid Bifurcation; Haemodynamics; Oscillatory Shear Index; Vascular geometry; Wall Shear Stress; BLOOD-FLOW; PULSATILE FLOW; DYNAMICS; EXPOSURE; STENOSIS;

D O I：

10.1016/j.clineuro.2024.108153

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objectives: The geometry of carotid bifurcation is a crucial contributing factor to the localization of atherosclerotic lesions. Currently, studies on carotid bifurcation geometry are limited to the region near to bifurcation. This study aimed to determine the influence of carotid bifurcation geometry on the blood flow using numerical simulations considering magnitude of haemodynamic parameters in the extended regions of carotid artery. Methods: In the present study, haemodynamic analysis is carried out using the non-Newtonian viscosity model for patient-specific geometries consisting of both Left and Right carotid arteries. A 3D patient-specific geometric model is generated using MIMICS, and a numerical model is created using ANSYS. Results: The results obtained from patient-specific cases are compared. The influence of geometric features such as lumen diameter, bifurcation angle, and tortuosity on the haemodynamics parameters such as velocity, WSS, pressure, Oscillatory Shear Index (OSI), and Time-Averaged Wall Shear Stress (TAWSS) are compared. Conclusion: The results demonstrate significant changes in the flow regime due to the geometric shape of the carotid artery. It is observed that the lower value of TAWSS occurs near the bifurcation region and carotid bulb region. In addition, the higher value of the (OSI) is observed in the Internal Carotid Artery (ICA) and the tortuous carotid artery region. However, it is also observed that apart from the bifurcation angle, other factors, such as tortuosity and area ratio, play a significant role in the flow dynamics of the carotid artery.

引用

页数：13

共 32 条

[1] Robust and objective decomposition and mapping of bifurcating vessels [J].

Antiga, L ;

Steinman, DA .

IEEE TRANSACTIONS ON MEDICAL IMAGING, 2004, 23 (06) :704-713

[2] Improved prediction of disturbed flow via hemodynamically-inspired geometric variables [J].

Bijari, Payam B. ;

Antiga, Luca ;

Gallo, Diego ;

Wasserman, Bruce A. ;

Steinman, David A. .

JOURNAL OF BIOMECHANICS, 2012, 45 (09) :1632-1637

[3] Assessment of Influences of Stenoses in Right Carotid Artery on Left Carotid Artery Using Wall Stress Marker [J].

Bit, Arindam ;

Ghagare, Dushali ;

Rizvanov, Albert A. ;

Chattopadhyay, Himadri .

BIOMED RESEARCH INTERNATIONAL, 2017, 2017

[4]

Domanin M, 2018, J VASC SURG, V67, P887, DOI 10.1016/j.jvs.2017.08.094

[5]

drzezo, 2019, Evaluating Carotid Plaque and Carotid Intima-Media Thickness, Radiology Key

[6] A coupled momentum method for modeling blood flow in three-dimensional deformable arteries [J].

Figueroa, C. Alberto ;

Vignon-Clementel, Irene E. ;

Jansen, Kenneth E. ;

Hughes, Thomas J. R. ;

Taylor, Charles A. .

COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 2006, 195 (41-43) :5685-5706

[7] Insights into the co-localization of magnitude-based versus direction-based indicators of disturbed shear at the carotid bifurcation [J].

Gallo, Diego ;

Steinman, David A. ;

Morbiducci, Umberto .

JOURNAL OF BIOMECHANICS, 2016, 49 (12) :2413-2419

[8] Helical flow in carotid bifurcation as surrogate marker of exposure to disturbed shear [J].

Gallo, Diego ;

Steinman, David A. ;

Bijari, Payam B. ;

Morbiducci, Umberto .

JOURNAL OF BIOMECHANICS, 2012, 45 (14) :2398-2404

[9]

Gharahi H, 2016, INT J ADV ENG SCI AP, V8, P46, DOI 10.1007/s12572-016-0161-6

[10]

Guerciotti B, 2018, LECT NOTES APPL COMP, V84, P169, DOI 10.1007/978-3-319-59548-1_10

← 1 2 3 4 →