Patient-reported outcome measures compared to clinician reported outcomes regarding incontinence and erectile dysfunction in localized prostate carcinoma after robot assisted radical prostatectomy: Impact on management

被引：3
作者：
Tillier, C. N. [1 ]
Boekhout, A. H. [2 ]
Veerman, H. [1 ,3 ]
Wollersheim, B. M. [2 ]
Groen, P. A. M. [1 ]
van der Poel, H. G. [1 ,3 ]
van de Poll-Franse, L. V. [2 ,4 ,5 ]
机构：
[1] Antoni Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Urol, Amsterdam, Netherlands
[2] Antoni Leeuwenhoek Hosp, Netherlands Canc Inst, Div Psychosocial Res & Epidemiol, Amsterdam, Netherlands
[3] Amsterdam Univ Med Ctr, Location VUMC, Dept Urol, Amsterdam, Netherlands
[4] Netherlands Comprehens Canc Org IKNL, Dept Res, Utrecht, Netherlands
[5] Tilburg Univ, CoRPS Ctr Res Psychol Somat Dis, Dept Med & Clin Psychol, Tilburg, Netherlands
来源：
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS | 2023年 / 41卷 / 11期
关键词：
Patient reported outcomes; Clinician reported outcomes; Prostate cancer; Radical prostatectomy; Assessment; Discrepancy; Management of incontinence; Management of erectile dysfunction; CANCER; RADIATION; SURGERY; THERAPY;
D O I：
10.1016/j.urolonc.2023.08.001
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Purpose/Background: Patient-reported outcome measures (PROMs) are widely used after robot assisted radical prostatectomy (RARP) in order to evaluate the impact/burden of the treatment. The most bothersome side effects of RARP are urine incontinence (UI) and erectile dysfunction (ED). During the follow up consultations, clinicians report these side effects in interviewing patients. Our study examined the discrepancy between the PROMs and clinician report outcomes (CROs) and hypothesized that the disagreement could have an impact on the management of UI and ED. Methods: Up to 1 year after RARP, UI and ED recovery of 312 men with localized and locally advanced prostate cancer were assessed using the International Consultation Incontinence Questionnaire Short-Form (ICIQ-SF) and the International Index of Erectile Function (IIEF-EF) and CROs by interview. Discrepancies between PROs and CROs were studied in light of treatment offered and management. Results: The ICIQ-SF Score matched with CROs in all sum score categories except in ICIQ sum score 6 to 12; here the UI was underre-ported by clinicians in 58% and 59% of patients at 8 and 12 months (P < 0.001). Furthermore, at 8 and 12 months postoperatively, clinicians underreported UI in 29% and 23% of patients with ICIQ score 13-18 (P < 0.001). The clinician significantly over-reported the recovery of erectile function ("normal erection") (P < 0.001), especially in men with IIEF-EF sum score 6 to 16. Independently of ICIQ-SF/IIEF-EF scores, discrepancy between PROs and CROs did not affect rate of health care offered to patients. Conclusions: This is to our knowledge the first study that compared the PROs with clinician reported functional outcomes and the impact of discrepancies on the management of side effects of RARP in prostate cancer. Observed discrepancies between the PROs and CROs did not affect offered management and counseling of UI and ED. (c) 2023 Elsevier Inc. All rights reserved.
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收藏
页码：454.e1 / 454.e8
页数：8
相关论文
共 19 条
[1]   Electronic patient-reported outcome systems in oncology clinical practice [J].
不详 .
CA-A CANCER JOURNAL FOR CLINICIANS, 2012, 62 (05) :336-347
[2]  
[Anonymous], Guidelines on Prostate Cancer
[3]  
AroraNK ReeveBB, JClinOncol2011, V29, P1280, DOI [10.1200/JCO.2010.32.1554:Epub2011Feb28, DOI 10.1200/JCO.2010.32.1554:EPUB2011FEB28]
[4]  
AveryK DonovanJ, NeurourolUrodyn2004, V23, P322
[5]   Association Between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes After 3 Years [J].
Barocas, Daniel A. ;
Alvarez, Joann ;
Resnick, Matthew J. ;
Koyama, Tatsuki ;
Hoffman, Karen E. ;
Tyson, Mark D. ;
Conwill, Ralph ;
McCollum, Dan ;
Cooperberg, Matthew R. ;
Goodman, Michael ;
Greenfield, Sheldon ;
Hamilton, Ann S. ;
Hashibe, Mia ;
Kaplan, Sherrie H. ;
Paddock, Lisa E. ;
Stroup, Antoinette M. ;
Wu, Xiao-Cheng ;
Penson, David F. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2017, 317 (11) :1126-1140
[6]  
BaschE IasonosA, LancetOncol2006, V7, P903, DOI [10.1016/S1470-2045, DOI 10.1016/S1470-2045]
[7]   Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer [J].
Donovan, J. L. ;
Hamdy, F. C. ;
Lane, J. A. ;
Mason, M. ;
Metcalfe, C. ;
Walsh, E. ;
Blazeby, J. M. ;
Peters, T. J. ;
Holding, P. ;
Bonnington, S. ;
Lennon, T. ;
Bradshaw, L. ;
Cooper, D. ;
Herbert, P. ;
Howson, J. ;
Jones, A. ;
Lyons, N. ;
Salter, E. ;
Thompson, P. ;
Tidball, S. ;
Blaikie, J. ;
Gray, C. ;
Bollina, P. ;
Catto, J. ;
Doble, A. ;
Doherty, A. ;
Gillatt, D. ;
Kockelbergh, R. ;
Kynaston, H. ;
Paul, A. ;
Powell, P. ;
Prescott, S. ;
Rosario, D. J. ;
Rowe, E. ;
Davis, M. ;
Turner, E. L. ;
Martin, R. M. ;
Neal, D. E. .
NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (15) :1425-1437
[8]   Prostate-specific health-related quality of life and patient-physician communication - A 3.5-year follow-up [J].
Ernstmann, Nicole ;
Herden, Jan ;
Weissbach, Lothar ;
Karger, Andre ;
Hower, Kira ;
Ansmann, Lena .
PATIENT EDUCATION AND COUNSELING, 2019, 102 (11) :2114-2121
[9]  
Gori Davide, 2019, EGEMS (Wash DC), V7, P43, DOI 10.5334/egems.297
[10]   Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer [J].
Hoffman, Karen E. ;
Penson, David F. ;
Zhao, Zhiguo ;
Huang, Li-Ching ;
Conwill, Ralph ;
Laviana, Aaron A. ;
Joyce, Daniel D. ;
Luckenbaugh, Amy N. ;
Goodman, Michael ;
Hamilton, Ann S. ;
Wu, Xiao-Cheng ;
Paddock, Lisa E. ;
Stroup, Antoinette ;
Cooperberg, Matthew R. ;
Hashibe, Mia ;
O'Neil, Brock B. ;
Kaplan, Sherrie H. ;
Greenfield, Sheldon ;
Koyama, Tatsuki ;
Barocas, Daniel A. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (02) :149-163
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