Polyvinyl Alcohol-Chitosan Scaffold for Tissue Engineering and Regenerative Medicine Application: A Review

被引：38

作者：

Nathan, Kavitha Ganesan ^{[1
]}

Genasan, Krishnamurithy ^{[2
]}

Kamarul, Tunku ^{[1
,3
]}

机构：

[1] Univ Malaya, Fac Med, Dept Orthoped Surg, Kuala Lumpur 50603, Malaysia

[2] Univ Malaya, Fac Med, Dept Physiol, Kuala Lumpur 50603, Malaysia

[3] Univ Sains Malaysia, Adv Med & Dent Inst AMDI, Bertam 13200, Kepala Batas, Malaysia

来源：

MARINE DRUGS | 2023年 / 21卷 / 05期

关键词：

polyvinyl alcohol; chitosan; scaffold; tissue engineering; regenerative medicine; MESENCHYMAL STEM-CELLS; POLY(VINYL ALCOHOL); CONTROLLED-RELEASE; CROSS-LINKING; CHONDROGENIC DIFFERENTIATION; MECHANICAL-PROPERTIES; NANOPARTICLES; DELIVERY; HYDROGEL; PVA;

D O I：

10.3390/md21050304

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Tissue engineering and regenerative medicine (TERM) holds great promise for addressing the growing need for innovative therapies to treat disease conditions. To achieve this, TERM relies on various strategies and techniques. The most prominent strategy is the development of a scaffold. Polyvinyl alcohol-chitosan (PVA-CS) scaffold emerged as a promising material in this field due to its biocompatibility, versatility, and ability to support cell growth and tissue regeneration. Preclinical studies showed that the PVA-CS scaffold can be fabricated and tailored to fit the specific needs of different tissues and organs. Additionally, PVA-CS can be combined with other materials and technologies to enhance its regenerative capabilities. Furthermore, PVA-CS represents a promising therapeutic solution for developing new and innovative TERM therapies. Therefore, in this review, we summarized the potential role and functions of PVA-CS in TERM applications.

引用

页数：18

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