Prognostic significance of Memorial Sloan-Kettering prognostic score in small-cell lung cancer patients

被引：0
作者：
Chen, Shuangqing [1 ,2 ]
Liu, Shicheng [1 ]
Kong, Lingxin [1 ,3 ]
Ren, Dahu [1 ,3 ]
Hu, Zhonghui [1 ]
Wu, Wenbo [1 ]
Duan, Guochen [1 ,4 ]
机构：
[1] Hebei Gen Hosp, Dept Thorac Surg, Shijiazhuang 050057, Peoples R China
[2] Hebei North Univ, Grad Sch, Zhangjiakou 075000, Peoples R China
[3] Hebei Med Univ, Grad Sch, Shijiazhuang 050011, Peoples R China
[4] Childrens Hosp Hebei Prov, Dept Thorac Surg, Shijiazhuang 050000, Peoples R China
来源：
BIOMARKERS IN MEDICINE | 2023年 / 17卷 / 07期
关键词：
biomarkers; neutrophil-to-lymphocyte ratio; nomogram predictive model; prognostic factor; small-cell lung cancer; NUTRITIONAL-STATUS; SURVIVAL; CEA; EXPRESSION; BIOMARKERS; PREDICT; IMPACT;
D O I：
10.2217/bmm-2023-0105
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Aim: To assess the potential factors with predictive value for survival in small-cell lung cancer (SCLC) patients and to develop a nomogram prediction model. Patients & methods: We retrospectively screened and analyzed patients with pathologically confirmed SCLC from April 2015 to December 2021. Results: A total of 167 patients with SCLC were included. According to the Memorial Sloan-Kettering prognostic score (MPS), patients were divided into three groups: group 0 (n = 65), group 1 (n = 69) and group 2 (n = 33). The multivariate analysis showed that MPS was an independent prognostic factor for progression-free and overall survival in SCLC patients (p < 0.05). The nomogram showed that MPS was the most influential factor for overall survival. Conclusion: MPS is an independent prognostic factor for overall and progression-free survival in SCLC patients and performed better than other indicators used in this study.
引用
收藏
页码：391 / 401
页数：11
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