MRI Digital Artery Volume Index (DAVIX) as a surrogate outcome measure of digital ulcer disease in patients with systemic sclerosis: a prospective cohort study

被引：12

作者：

Hughes, Michael ^{[1
,2
]}

Di Donato, Stefano ^{[3
]}

Gjeloshi, Klodian ^{[4
]}

Abignano, Giuseppina ^{[5
]}

Danzo, Fiammetta ^{[6
]}

Lettieri, Giovanni ^{[5
]}

De Lorenzis, Enrico ^{[3
,7
]}

Bertham, Dominic ^{[8
]}

O'Connor, Philip ^{[3
,8
]}

Kubassova, Olga ^{[9
]}

Dehmeshki, Jamshid ^{[9
,10
]}

Del Galdo, Francesco ^{[3
,8
,11
]}

机构：

[1] Tameside & Glossop Integrated Care NHS Fdn Trust, Dept Rheumatol, Ashton Under Lyne, England

[2] Univ Manchester, Fac Biol Med & Hlth, Manchester, England

[3] Univ Leeds, Leeds Inst Rheumat & Musculoskeletal Med, Leeds, England

[4] Univ Campania Luigi Vanvitelli, Dept Adv Med & Surg Sci, Naples, Italy

[5] Ist Reumatol Lucano, Azienda Osped Reg San Carlo, Potenza, Italy

[6] Univ Milan, Osped L Sacco, Dept Biomed & Clin Sci, Div Resp Dis,ASST Fatebenefratelli Sacco, Milan, Italy

[7] Univ Cattolica Sacro Cuore, Fdn Policlin Univ Gemelli IRCCS, Div Rheumatol, Rome, Italy

[8] Leeds Teaching Hosp NHS Trust, NIHR Leeds Biomed Res Ctr, Leeds, England

[9] Image Anal Grp, London, England

[10] Kingston Univ, Dept Comp Sci, London, England

[11] Univ Leeds, Leeds Inst Rheumat & Musculoskeletal Med, Leeds LS7 4SA, England

来源：

LANCET RHEUMATOLOGY | 2023年 / 5卷 / 10期

关键词：

Manchester; UK (M Hughes); MAGNETIC-RESONANCE ANGIOGRAPHY; RAYNAUDS-PHENOMENON; SCLERODERMA; CLASSIFICATION; SCALE;

D O I：

10.1016/S2665-9913(23)00189-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background Vascular fibrosis is a key manifestation of systemic sclerosis that leads to the narrowing of small and medium arteries, causing vascular clinical manifestations including digital ulcers and pulmonary arterial hypertension. We investigated the potential of the MRI-based Digital Artery Volume Index (DAVIX) as a surrogate outcome measure of vascular fibrosis by using it to quantify and predict the burden of digital ulcer disease in patients with systemic sclerosis.

引用

页码：e611 / e621

页数：11

共 31 条

[1] SEEDED REGION GROWING [J].