Neuromuscular Blocking Agents in the Intensive Care Unit

Purpose of ReviewThe purpose of this review is to recognize common complications associated with the use of neuromuscular blocking agents in critically ill patients.Recent FindingsNeuromuscular blocking agents have been commonly used in the operating room to facilitate endotracheal intubation and improve surgical outcomes. Similarly, neuromuscular blocking agents in the intensive care unit have been frequently used in critically ill patients who require advanced ventilatory and respiratory support. Intensive care unit-acquired weakness, hypoxia, and respiratory adverse events associated with residual neuromuscular blockade are common complications seen with the use of neuromuscular blocking agents in the intensive care unit.SummaryNeuromuscular blockade is a common practice in the intensive care unit, especially, in patients who require endotracheal intubation and mechanical ventilation. However, complications have been documented in critically ill patients while receiving neuromuscular blocking agents and this patient population warrants special considerations.