Risk of cerebrovascular disease after cancer diagnosis in the United States

被引:2
作者
Liu, Qiang [1 ]
Zhang, Wenxiang [1 ]
Li, Qi [1 ]
Chen, Li [2 ]
Wang, Xiangyu [1 ]
Wang, Zhongzhao [1 ]
Wang, Yipeng [1 ]
Wang, Jing [1 ]
机构
[1] Chinese Acad Med Sci & Peking Union Med Coll, Canc Hosp, Natl Canc Ctr, Natl Clin Res Ctr Canc,Dept Breast Surg Oncol, Beijing 100021, Peoples R China
[2] Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Thyroid & Breast Surg, Wuhan 430030, Hubei, Peoples R China
关键词
ISCHEMIC-STROKE; HEART-DISEASE; WOMEN; RADIOTHERAPY;
D O I
10.1016/j.isci.2023.107165
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The risk of subsequent cerebrovascular disease among cancer patients of multiple cancers in the US is not well understood. A total of 3,843,261 cancer patients diagnosed from 1975 to 2018, were included from the surveillance, epidemiology, and end results (SEER) database. Standardized mortality ratios (SMRs) and absolute excess risks (AERs) were estimated. The overall cerebrovascular disease SMR was 1.04 (95% CI, 1.03-1.04), and the AER per 10,000 person-years at risk was 0.89. When compared with the US general population, greater cerebrovascular disease risk was correlated with certain cancer sites, American Indian/Alaska Native race, Asian or Pacific Islander race, unmarried marital status, distant metastasis, younger age, and an earlier time of cancer diagnosis. Clinically, more precision and proactive strategies for cerebrovascular disease prevention are required to subgroup of cancer patients with a greater risk of cerebrovascular disease, especially within the first two months.
引用
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页数:16
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