Anorectal melanoma

被引:4
|
作者
Fastner, Suzanne [1 ]
Hieken, Tina J. J. [2 ]
McWilliams, Robert R. R. [3 ]
Hyngstrom, John [1 ,4 ,5 ]
机构
[1] Huntsman Canc Inst, Salt Lake City, UT USA
[2] Mayo Clin, Dept Surg, Div Breast & Melanoma Surg Oncol, Rochester, MN USA
[3] Mayo Clin, Dept Oncol, Rochester, MN USA
[4] Univ Utah, Dept Surg, Div Surg Oncol, Salt Lake City, UT USA
[5] Univ Utah Hlth, Huntsman Canc Hosp, 1950 Cirof Hope Dr, Salt Lake City, UT 84132 USA
关键词
adjuvant; anorectal melanoma; immunotherapy; local excision; melanoma; mucosal melanoma; proctectomy; radiotherapy; SPARING LOCAL EXCISION; RESECTED STAGE-III; MUCOSAL MELANOMA; ADJUVANT RADIATION; RECTAL MELANOMA; MANAGEMENT; NIVOLUMAB; SURVIVAL; IPILIMUMAB; THERAPY;
D O I
10.1002/jso.27381
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Anorectal melanoma is an aggressive mucosal melanoma subtype with a poor prognosis. Although recent advancements have been seen for cutaneous melanoma, the optimal treatment paradigm for management of anorectal melanoma is evolving. In this review, we highlight differences in the pathogenesis of mucosal versus cutaneous melanoma, new concepts of staging for mucosal melanoma, updates to surgical management of anorectal melanoma, and current data for adjuvant radiation and systemic therapy in this unique patient population.
引用
收藏
页码:635 / 644
页数:10
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