Oxidative (3+3) Cycloaddition/Ring-Opening Reactions of Simple Urea Derivatives and N,N′-Cyclic Azomethine Imines to Construct 1,2,3,5-Tetrazine-4(1H)-one Derivatives

被引：2
作者：
He, Zhao-Lin [1 ]
Tian, Wen [1 ]
Wang, Gang [1 ]
机构：
[1] Wuhan Inst Technol, Engn Res Ctr Phosphorus Resources Dev & Utilizat, Sch Chem & Environm Engn, Hubei Key Lab Novel Reactor & Green Chem Technol,K, Wuhan 430205, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 13期
基金：
中国国家自然科学基金;
关键词：
1,3-DIPOLAR CYCLOADDITION; NITRILE IMINES; YLIDES; ANNULATION; ALKALOIDS; DESIGN; ACCESS; ROUTE;
D O I：
10.1021/acs.joc.3c00525
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A noveloxidative (3 + 3) cycloaddition/ring-opening reaction of N,N '-cyclic azomethine imines withthe in situ generated diaza-oxylallyl cations from simple urea derivativesin the presence of base and PhI(OAc)(2) has been developed.This transformation performs well over a broad substrate scope, whichprovides facile and rapid access to 1,2,3,5-tetrazine-4(1H)-one derivatives in good yields.
引用
收藏
页码：8609 / 8618
页数：10
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