A review on the role of LINC00511 in cancer

被引:9
作者
Ghafouri-Fard, Soudeh [1 ]
Safarzadeh, Arash [2 ]
Hussen, Bashdar Mahmud [3 ]
Taheri, Mohammad [4 ,5 ]
Ayatollahi, Seyed Abdulmajid [6 ]
机构
[1] Shahid Beheshti Univ Med Sci, Sch Med, Dept Med Genet, Tehran, Iran
[2] Shahid Beheshti Univ Med Sci, Mens Hlth & Reprod Hlth Res Ctr, Tehran, Iran
[3] Hawler Med Univ, Coll Pharm, Dept Clin Anal, Erbil, Iraq
[4] Jena Univ Hosp, Inst Human Genet, Jena, Germany
[5] Shahid Beheshti Univ Med Sci, Urol & Nephrol Res Ctr, Tehran, Iran
[6] Shahid Beheshti Univ Med Sci, Phytochem Res Ctr, Tehran, Iran
关键词
LINC00511; cancer; biomarker; expression; diagnostic; NONCODING RNA LINC00511; SQUAMOUS-CELL CARCINOMA; UP-REGULATION; LUNG-CANCER; PROLIFERATION; EXPRESSION; PROGRESSION; PROMOTES; INVASION; CONTRIBUTES;
D O I
10.3389/fgene.2023.1116445
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Long Intergenic Non-Protein Coding RNA 511 (LINC00511) is an RNA gene being mostly associated with lung cancer. Further assessments have shown dysregulation of this lncRNA in a variety of cancers. LINC00511 has interactions with hsa-miR-29b-3p, hsa-miR-765, hsa-mir-150, miR-1231, TFAP2A-AS2, hsa-miR-185-3p, hsa-miR-29b-1-5p, hsa-miR-29c-3p, RAD51-AS1 and EZH2. A number of transcription factors have been identified that regulate expression of LINC00511. The current narrative review summarizes the role of LINC00511 in different cancers with an especial focus on its prognostic impact in human cancers.
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页数:13
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