One-year outcomes in cardiogenic shock triggered by ventricular arrhythmia: An analysis of the FRENSHOCK multicenter prospective registry

被引:5
作者
Cherbi, Miloud [1 ,2 ]
Roubille, Francois [3 ]
Lamblin, Nicolas [4 ]
Bonello, Laurent [5 ,6 ,7 ]
Leurent, Guillaume [8 ]
Levy, Bruno [9 ]
Elbaz, Meyer [1 ,2 ]
Champion, Sebastien [10 ]
Lim, Pascal [11 ,12 ]
Schneider, Francis [13 ]
Cariou, Alain [14 ]
Khachab, Hadi [15 ]
Bourenne, Jeremy [16 ]
Seronde, Marie-France [17 ]
Schurtz, Guillaume [4 ]
Harbaoui, Brahim [18 ,19 ,20 ]
Vanzetto, Gerald [21 ]
Quentin, Charlotte [22 ]
Delabranche, Xavier [23 ]
Aissaoui, Nadia [15 ]
Combaret, Nicolas [24 ]
Tomasevic, Danka [25 ]
Marchandot, Benjamin [26 ]
Lattuca, Benoit [27 ]
Henry, Patrick [28 ]
Gerbaud, Edouard [29 ,30 ]
Bonnefoy, Eric [25 ]
Puymirat, Etienne [31 ,32 ]
Maury, Philippe [1 ,2 ]
Delmas, Clement [1 ,2 ]
机构
[1] Rangueil Univ Hosp, Intens Cardiac Care Unit, Toulouse, France
[2] Natl Inst Hlth & Med Res INSERM, Inst Metab & Cardiovasc Dis I2MC, UMR 1048, Toulouse, France
[3] Univ Montpellier, Cardiol Dept, PhyMedExp, INSERM,CNRS,INI CRT,CHU Montpellier, Montpellier, France
[4] Univ Lille, Dept Cardiol Urgences & Soins Intens Cardiol, CHU Lille, Inserm,U1167, Lille, France
[5] Aix Marseille Univ, Marseille, France
[6] Hop Nord Marseille, AP HM, Dept Cardiol, Intens Care Unit, Marseille, France
[7] Mediterranean Assoc Res & Studies Cardiol MARS Car, Marseille, France
[8] Univ Rennes 1, Dept Cardiol, CHU Rennes, Inserm,LTSI,UMR 1099, Rennes, France
[9] CHRU Nancy, Reanimat Med Brabois, Nancy, France
[10] CHU Toulouse, Inst St Jacques, REICATRA, Le Chesnay, France
[11] Univ Paris Est Creteil, INSERM, IMRB, Creteil, France
[12] Hop Univ Henri Mondor, AP HP, Serv Cardiol, Creteil, France
[13] Hop Univ Strasbourg, Hop Hautepierre, Med Intens Reanimat, Strasbourg, France
[14] Ctr Univ Paris, Cochin Hosp, AP HP, Med Sch,Med Intens Care Unit, Paris, France
[15] CH Aix En Provence, Dept Cardiol, Intens Cardiac Care Unit, Aix En Provence, France
[16] Aix Marseille Univ, Serv Reanimat Urgences, CHU La Timone 2, Marseille, France
[17] CHU Besancon, Serv Cardiol, Besancon, France
[18] Hop Croix Rousse, Hop Lyon Sud, Cardiol Dept, Hosp Civils Lyon, Lyon, France
[19] Hosp Civils Lyon, Hop Lyon Sud, Lyon, France
[20] Univ Lyon, Dept Cardiol, CREATIS, INSERM,U1044,UMR5220,INSA 15, Lyon, France
[21] Hop Grenoble, Dept Cardiol, Grenoble, France
[22] Ctr Hosp Broussais, Serv Reanimat Polyvalente, 1 Rue Marne, St Malo, France
[23] Les Hop Univ Strasbourg, Nouvel Hop Civil 1, Porte Hop, Reanimat Chirurg Polyvalente,Pole Anesthesie Reani, Strasbourg, France
[24] Univ Clermont Auvergne, Dept Cardiol, CHU Clermont Ferrand, CNRS, Clermont Ferrand, France
[25] Lyon Brom Univ Hosp, Intens Cardiac Care Unit, Lyon, France
[26] Univ Strasbourg, Nouvel Hop Civil, CHU Strasbourg, Pole Act Medicochirurg Cardiovasc, Strasbourg, France
[27] Univ Montpellier, Nimes Univ Hosp, Dept Cardiol, Nimes, France
[28] Hop Lariboisiere, AP HP, Dept Cardiol, Paris, France
[29] Hop Cardiol Haut Leveque, Intens Cardiac Care Unit & Intervent Cardiol, Pessac, France
[30] Bordeaux Univ, Hop Xavier Arnozan, Bordeaux Cardiothorac Res Ctr, U1045, Pessac, France
[31] Hop Europeen Georges Pompidou, AP HP, Dept Cardiol, Paris, France
[32] Univ Paris, Paris, France
来源
FRONTIERS IN CARDIOVASCULAR MEDICINE | 2023年 / 10卷
关键词
cardiogenic shock; ventricular tachycardia; ventricular arrhythmia; epidemiology; prognosis; IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR; CARDIAC RESYNCHRONIZATION; CARDIOMYOPATHY PATIENTS; DILATED CARDIOMYOPATHY; SHORT-TERM; MORTALITY; ABLATION;
D O I
10.3389/fcvm.2023.1092904
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Cardiogenic shock (CS) is a life-threatening condition carrying poor prognosis, potentially triggered by ventricular arrhythmia (VA). Whether the occurrence of VA as trigger of CS worsens the prognosis compared to non-VA triggers remains unclear. The aim of this study was to evaluate 1-year outcomes [mortality, heart transplantation, ventricular assist devices (VAD)] between VA-triggered and non-VA-triggered CS.Methods: FRENSHOCK is a prospective multicenter registry including 772 CS patients from 49 centers. One to three triggers can be identified in the registry (ischemic, mechanical complications, ventricular/supraventricular arrhythmia, bradycardia, iatrogenesis, infection, non-compliance). Baseline characteristics, management and 1-year outcomes were analyzed according to the VA-trigger in the CS population.Results: Within 769 CS patients included, 94 were VA-triggered (12.2%) and were compared to others. At 1 year, although there was no mortality difference [42.6 vs. 45.3%, HR 0.94 (0.67-1.30), p = 0.7], VA-triggered CS resulted in more heart transplantations and VAD (17 vs. 9%, p = 0.02). Into VA-triggered CS group, though there was no 1-year mortality difference between ischemic and non-ischemic cardiomyopathies [42.5 vs. 42.6%, HR 0.97 (0.52-1.81), p = 0.92], non-ischemic cardiomyopathy led to more heart transplantations and VAD (25.9 vs. 5%, p = 0.02).Conclusion: VA-triggered CS did not show higher mortality compared to other triggers but resulted in more heart transplantation and VAD at 1 year, especially in non-ischemic cardiomyopathy, suggesting the need for earlier evaluation by advanced heart failure specialized team for a possible indication of mechanical circulatory support or heart transplantation.
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页数:11
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