Treatment of Patients with Mild to Moderate Ulcerative Colitis: A Middle East Expert Consensus

被引:2
|
作者
Al Awadhi, Sameer [1 ]
Alboraie, Mohamed [2 ]
Albaba, Emad Aldin [3 ]
Almutairdi, Abdulelah [4 ]
Alsaad, Monther [5 ]
Azzam, Nahla [6 ]
Barakat, Husam [7 ]
D'Amico, Ferdinando [8 ,9 ,10 ]
Danese, Silvio [8 ,9 ]
El Kady, Mohamed [11 ]
Ghoneim, Hossam [12 ]
Hamoudi, Waseem [13 ]
Jazzar, Ahmad [14 ]
Mosli, Mahmoud [15 ]
Shehab, Hany [16 ]
Sneineh, Awni Abu [17 ]
机构
[1] Rashid Hosp, Digest Dis Unit, Dubai 003206, U Arab Emirates
[2] Al Azhar Univ, Dept Internal Med, Cairo 11884, Egypt
[3] Almana Gen Hosp, Dept Med, Al Khobar 31952, Saudi Arabia
[4] King Faisal Specialist Hosp & Res Ctr, Dept Med, Riyadh 11564, Saudi Arabia
[5] Al Madar Med Ctr, POB 80789, Sharjah, U Arab Emirates
[6] King Saud Univ, Coll Med, Dept Med, Div Gastroenterol, Riyadh 11451, Saudi Arabia
[7] Yarmouk Univ, Dept Gastroenterol, Irbid 21163, Jordan
[8] IRCCS Osped San Raffaele, Gastroenterol & Endoscopy, I-20132 Milan, Italy
[9] Univ Vita Salute San Raffaele, I-20132 Milan, Italy
[10] Humanitas Univ, Dept Biomed Sci, I-20132 Milan, Italy
[11] Cairo Univ, Fac Med, Dept Med Pharmacol, Cairo 11559, Egypt
[12] Alexandria Univ, Med Res Inst, Immunol & Allergy Dept, Alexandria 5424041, Egypt
[13] Al Bashir Hosp, Internal Med Dept, Amman 11151, Jordan
[14] Sheikh Khalifa Med City, Gastroenterol Div, Abu Dhabi 51900, U Arab Emirates
[15] King Abdulaziz Univ Hosp, Dept Med, Jeddah 21589, Saudi Arabia
[16] Cairo Univ, Integrated Clin & Res Ctr Intestinal Disorders IC, Endem Med Dept, Gastroenterol Div, Cairo 3725121, Egypt
[17] Univ Jordan, Gastroenterol & Hepatol, Amman 11942, Jordan
关键词
5-ASA; mesalazine; budesonide MMX; ulcerative colitis; inflammatory bowel disease; RANDOMIZED CLINICAL-TRIAL; INFLAMMATORY-BOWEL-DISEASE; VS; 2.4; G/DAY; ORAL MESALAZINE; TOPICAL; 5-AMINOSALICYLATES; DOUBLE-BLIND; MAINTENANCE; REMISSION; EFFICACY; GUIDELINES;
D O I
10.3390/jcm12216929
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The prevalence of ulcerative colitis (UC) in the Middle East is increasing, impacting the economic and healthcare burden. The management of patients with mild to moderate UC is still a challenge as several factors can affect optimal care, including drug choice, induction and maintenance dose, treatment optimization and de-escalation, therapy duration, monitoring, and safety profile. We conducted an expert consensus to standardize the management of patients with mild to moderate UC. Sixteen experts in inflammatory bowel diseases, through a well-established and accepted Delphi methodology, voted and approved eight statements in order to provide practical guidance to clinicians in the Middle East.
引用
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页数:11
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