COVID-19 and cardiovascular disease in patients with chronic kidney disease

被引：12

作者：

Del Vecchio, Lucia ^{[1
]}

Balafa, Olga ^{[2
]}

Dounousi, Evangelia ^{[3
]}

Ekart, Robert ^{[4
]}

Fernandez, Beatriz Fernandez ^{[5
]}

Mark, Patrick B. ^{[6
]}

Sarafidis, Pantelis ^{[7
]}

Valdivielso, Jose M. ^{[8
]}

Ferro, Charles J. ^{[9
,10
]}

Mallamaci, Francesca ^{[11
,12
]}

机构：

[1] ASST Lariana, Dept Nephrol & Dialysis, St Anna Hosp, Como, Italy

[2] Univ Hosp Ioannina, Dept Nephrol, Ioannina, Greece

[3] Univ Ioannina, Fac Med, Sch Hlth Sci, Dept Nephrol, Ioannina, Greece

[4] Univ Med Ctr Maribor, Dept Dialysis, Clin Internal Med, Maribor, Slovenia

[5] IIS Fdn Jimenez Diaz UAM, Dept Nephrol & Hypertens, Madrid, Spain

[6] Univ Glasgow, Sch Cardiovasc & Metab Hlth, Glasgow, Scotland

[7] Aristotle Univ Thessaloniki, Hippokration Hosp, Dept Nephrol 1, Thessaloniki, Greece

[8] Inst Biomed Res Lleida IRBLleida, Vasc & Renal Translat Res Grp, Lleida, Spain

[9] Univ Birmingham, Univ Hosp Birmingham, Dept Renal Med, Birmingham, England

[10] Univ Birmingham, Inst Cardiovasc Sci, Birmingham, England

[11] Azienda Osped Bianchi Melacrino Morelli, Francesca Mallamaci Dept Nephrol Dialysis & Trans, Reggio Di Calabria, Italy

[12] CNR IFC, Reggio Di Calabria, Italy

来源：

NEPHROLOGY DIALYSIS TRANSPLANTATION | 2024年 / 39卷 / 02期

关键词：

cardiovascular disease; chronic kidney disease; COVID-19; post-COVID syndrome; SARS-Cov2; ANGIOTENSIN-SYSTEM INHIBITORS; CLINICAL CHARACTERISTICS; OPEN-LABEL; D-DIMER; HEMODIALYSIS-PATIENTS; SARS-COV-2; INFECTS; RISK-FACTORS; ALL-CAUSE; ANTICOAGULATION; MULTICENTER;

D O I：

10.1093/ndt/gfad170

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

Millions of people worldwide have chronic kidney disease (CKD). Affected patients are at high risk for cardiovascular (CV) disease for several reasons. Among various comorbidities, CKD is associated with the more severe forms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This is particularly true for patients receiving dialysis or for kidney recipients. From the start of the SARS-CoV-2 pandemic, several CV complications have been observed in affected subjects, spanning acute inflammatory manifestations, CV events, thrombotic episodes and arrythmias. Several pathogenetic mechanisms have been hypothesized, including direct cytopathic viral effects on the myocardium, endothelial damage and hypercoagulability. This spectrum of disease can occur during the acute phase of the infection, but also months after recovery. This review is focussed on the CV complications of coronavirus disease 2019 (COVID-19) with particular interest in their implications for the CKD population.

引用

页码：177 / 189

页数：13

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