Ketogenic diet in cancer management

被引:9
作者
Talib, Wamidh H. [1 ,4 ]
Al-Dalaeen, Anfal [2 ]
Mahmod, Asma Ismail [3 ]
机构
[1] Appl Sci Private Univ, Fac Allied Med Sci, Amman, Jordan
[2] Appl Sci Private Univ, Fac Allied Med Sci, Dept Clin Nutr & Dietet, Amman, Jordan
[3] Appl Sci Private Univ, Dept Clin Pharm & Therapeut, Amman, Jordan
[4] Appl Sci Private Univ, Amman 11931166, Jordan
关键词
cancer metabolism; dietary intervention; high fat diet; Warburg effect; LUNG-CANCER; ATKINS DIET; METABOLISM; EFFICACY; THERAPY; CXCL12; MICE;
D O I
10.1097/MCO.0000000000000944
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of reviewThis review presents details about types of ketogenic diet (KD), anticancer mechanisms, and the use of KD in experimental and clinical studies. Studies summarized in this review provide a solid ground for researchers to consider the use of KD to augment conventional treatments.Recent findingsKD is a dietary pattern composed of high fat, moderate proteins, and very-low-carbohydrate. This diet was suggested to have an anticancer effect and to augment conventional anticancer therapies. KD can target cancer cell by interfering with its metabolism without harming normal cells.Several experimental and clinical studies support the use of KD as adjuvant therapy to treat different cancers.
引用
收藏
页码:369 / 376
页数:8
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