Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy

被引：4
|
作者：
Wang, Guan
Wu, Yongya
Wu, Chengyong
Shuai, Wen
Jiang, Tingting
Wang, Aoxue
Bu, Faqian
Sun, Qiu [1 ]
Ouyang, Liang [1 ]
机构：
[1] Sichuan Univ, West China Hosp, Natl Clin Res Ctr Geriatr, State Key Lab Biotherapy, Chengdu 610041, Peoples R China
来源：
ACTA PHARMACEUTICA SINICA B | 2023年 / 13卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Cancer therapy; Co-crystal structure; Drug discovery; Selective inhibitor; TRKA;
D O I：
10.1016/j.apsb.2022.10.012
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：440 / 443
页数：4
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