Efficacy of ceramide-containing sunscreen on skin barrier

BackgroundUV rays not only cause oxidative damage to the skin, but also damage its barrier function. The use of sunscreen is crucial in preventing skin from UV radiation, but it may have an impact on the function of the skin barrier. While much research has focused on the protective effects of sunscreen against UV oxidative damage, little is known about the impact of daily sunscreen use on the skin barrier.ObjectiveThis study mainly investigated the changes in skin barrier function of volunteers (including those with sensitive skin) before and after using a ceramide-containing sunscreen.MethodsA total of 60 volunteers used SPF30 sunscreen containing ceramide every morning. Using non-invasive methods to detect skin barrier changes in TEWL, hydration, facial redness based on VISIA-CR image, and Erythema index (EI) value after 4 weeks of using ceramide-containing sunscreen. Adverse reactions were also assessed.ResultsAfter 4 weeks of using ceramide-containing sunscreen, significant reductions were observed in skin redness with both an 11.89% decrease in a* value and a 5.68% decrease in skin EI, while there was also a significant decrease in transepidermal water loss (TEWL) with a reduction of 22.96%, and a significant increase in skin hydration with a 21.96% increase in the moisture content of the stratum corneum. No adverse events occurred during the entire testing process.ConclusionDaily application of ceramide-containing sunscreen can increase skin hydration while enhancing the function of the skin barrier.