Putting aging on ICE

被引：1

作者：

Teefy, Bryan B. ^{[1
]}

Benayoun, Berenice A. ^{[1
,2
,3
,4
,5
]}

机构：

[1] Univ Southern Calif, Leonard Davis Sch Gerontol, Los Angeles, CA 90089 USA

[2] USC Dornsife Coll Letters Arts & Sci, Mol & Computat Biol Dept, Los Angeles, CA 90089 USA

[3] USC Keck Sch Med, Biochem & Mol Med Dept, Los Angeles, CA 90089 USA

[4] USC Norris Comprehens Canc Ctr, Epigenet & Gene Regulat, Los Angeles, CA 90089 USA

[5] USC Stem Cell Initiat, Los Angeles, CA 90089 USA

来源：

CELL METABOLISM | 2023年 / 35卷 / 03期

关键词：

CHROMATIN;

D O I：

10.1016/j.cmet.2023.02.012

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A recent report by Yang et al. in Cell demonstrates that faithful DNA double-strand breaks and repair cycles phenocopy many aspects of aging in mice. Whether this progeroid phenotype is caused by a loss of epige-netic information remains to be conclusively determined.

引用

页码：383 / 385

页数：3

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