The Role of Vitamin D in Autoimmune Thyroid Diseases: A Narrative Review

被引：20

作者：

Czarnywojtek, Agata ^{[1
,2
]}

Florek, Ewa ^{[3
]}

Pietronczyk, Krzysztof ^{[4
]}

Sawicka-Gutaj, Nadia ^{[2
]}

Ruchala, Marek ^{[2
]}

Ronen, Ohad ^{[5
]}

Nixon, Iain J. ^{[6
]}

Shaha, Ashok R. ^{[7
]}

Rodrigo, Juan Pablo ^{[8
,9
]}

Tufano, Ralph Patrick ^{[10
]}

Zafereo, Mark ^{[11
]}

Randolph, Gregory William ^{[12
]}

Ferlito, Alfio

机构：

[1] Poznan Univ Med Sci, Dept Pharmacol, PL-60806 Poznan, Poland

[2] Poznan Univ Med Sci, Chair Dept Endocrinol Metab & Internal Med, PL-60355 Poznan, Poland

[3] Poznan Univ Med Sci, Dept Toxicol, Lab Environm Res, Dojazd 30 St, PL-60631 Poznan, Poland

[4] Voivodal Specialist Hosp Olsztyn, PL-10561 Olsztyn, Poland

[5] Bar Ilan Univ, Azrieli Fac Med, Galilee Med Ctr, Dept Otolaryngol Head & Neck Surg, IL-5290002 Tel Awiw, Israel

[6] Edinburgh Royal Infirm, Dept Otorhinolaryngol Head & Neck Surg, Edinburgh EH8 9YL, Scotland

[7] Mem Sloan Kettering Canc Ctr, Head & Neck Serv, New York, NY 10065 USA

[8] Univ Oviedo, Hosp Univ Cent Asturias, Fdn Invest Innovac Biosanit Principado Asturias, Dept Otolaryngol, Oviedo 33011, Spain

[9] Univ Oviedo, Inst Univ Oncol Principadode Asturias, Oviedo 33011, Spain

[10] Sarasota Mem Hlth Care Syst, Multidisciplinary Thyroid & Parathyroid Ctr Head &, Sarasota, FL 34239 USA

[11] MD Anderson Canc Ctr, Dept Head & Neck Surg, Houston, TX 77005 USA

[12] Harvard Med Sch, Dept Otolaryngol Head & Neck Surg, Boston, MA 02114 USA

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 04期

关键词：

vitamin D; Hashimoto thyroiditis; Graves' disease; Riedel thyroiditis; postpartum thyroiditis; SERUM 25-HYDROXYVITAMIN D; D DEFICIENCY; D LEVEL; HASHIMOTOS-THYROIDITIS; GRAVES-DISEASE; RHEUMATOID-ARTHRITIS; D ABSORPTION; ASSOCIATION; CHILDREN; HEALTH;

D O I：

10.3390/jcm12041452

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Vitamin D (VitD) deficiency has garnered significant attention in contemporary medical research. Although the canonical biological activity of VitD manifests itself mainly in the regulation of calcium-phosphorus metabolism, recent studies show that, thanks to the presence of numerous receptors, VitD may also play an important role in regulating the immune system. VitD deficiency has been demonstrated to impact autoimmune disease, coeliac disease, infections (including respiratory/COVID-19), and patients with cancer. Recent studies also show that VitD plays a significant role in autoimmune thyroid diseases (AITDs). Many studies have shown a correlation between low VitD levels and chronic autoimmune thyroiditis - Hashimoto thyroiditis (HT), Graves' disease (GD), and postpartum thyroiditis (PPT). This review article, therefore, describes the current state of knowledge on the role of VitD in AITDs, including HT, GD, and PTT.

引用

页数：12

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