Dynamic plasmid copy number control for synthetic biology

被引：2
作者：
Wang, Gege [1 ]
Wang, Qi [1 ]
Qi, Qingsheng [1 ]
Wang, Qian [1 ]
机构：
[1] Shandong Univ, Natl Glycoengn Res Ctr, State Key Lab Microbial Technol, Qingdao, Peoples R China
来源：
TRENDS IN BIOTECHNOLOGY | 2024年 / 42卷 / 02期
基金：
中国国家自然科学基金; 国家重点研发计划;
关键词：
This work was supported by the National Key R&D Program of China ( 2019YFA0904900 ) and the National Natural Science Foundation of China ( No. 32270089 );
D O I：
10.1016/j.tibtech.2023.08.004
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Plasmids that replicate independently from chromosomes are valuable genetic tools for biological research. Dynamic control of plasmid copy number facilitates flexible regulation of the gene of interest or the genetic circuit installed in the plasmid. This useful strategy is being integrated into synthetic biology for metabolic reprogramming and biosensing applications.
引用
收藏
页码：147 / 150
页数：4
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