Effect of tezepelumab in patients with severe, uncontrolled asthma by age of onset, allergic status, and eosinophilic phenotype

被引：1
|
作者：
Mathur, S. K. [1 ]
Hill, J. L. [2 ,3 ]
Ambrose, C. S. [4 ]
Martin, N. [5 ,6 ,8 ,9 ]
Llanos, J-P [7 ]
Martin, N. [5 ,6 ,8 ,9 ]
Colice, G. [10 ]
机构：
[1] Univ Wisconsin, Dept Med, Div Allergy Pulm & Crit Care Med, Madison, WI USA
[2] San Tan Allergy & Asthma, Arizona Allergy & Immunol Res, Gilbert, AZ USA
[3] Arcadia Allergy & Asthma, Phoenix, AZ USA
[4] AstraZeneca, Resp & Immunol, BioPharmaceut Med, Gaithersburg, MD USA
[5] AstraZeneca, BioPharmaceut RandD, Resp & Immunol, Biometr,Late Stage Dev, Waltham, MA USA
[6] Cytel Inc, Waltham, MA USA
[7] Amgen Inc, Global Med Affairs, Thousand Oaks, CA USA
[8] AstraZeneca, Resp & Immunol, BioPharmaceut Med, Cambridge, England
[9] Univ Leicester, Leicester, Leics, England
[10] AstraZeneca, Late Stage Dev, Resp & Immunol, BioPharmaceut RandD, Gaithersburg, MD USA
来源：
THORAX | 2023年 / 78卷 / SUPPL_4期
关键词：
D O I：
10.1136/thorax-2023-BTSabstracts.125
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
S119
引用
收藏
页码：A86 / A86
页数：1
相关论文
共 50 条
  • [41] Tezepelumab reduces exacerbations across all seasons in patients with severe, uncontrolled asthma (NAVIGATOR)
    Pavord, Ian D.
    Hoyte, Flavia C. L.
    Lindsley, Andrew W.
    Ambrose, Christopher S.
    Spahn, Joseph D.
    Roseti, Stephanie L.
    Cook, Bill
    Grif, Janet M.
    Hellqvist, Asa
    Martin, Nicole
    Llanos, Jean-Pierre
    Martin, Neil
    Colice, Gene
    Corren, Jonathan
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2023, 131 (05) : 587 - 597.e3
  • [42] Characteristics of exacerbations in patients with severe, uncontrolled asthma who received tezepelumab versus placebo
    Bourdin, Arnaud
    Wechsler, Michael E.
    Brightling, Christopher E.
    Korn, Stephanie
    Brusselle, Guy
    Heaney, Liam G.
    Ponnarambil, Sandhia
    Hunter, Gillian
    Lindsley, Andrew W.
    Ambrose, Christopher S.
    EUROPEAN RESPIRATORY JOURNAL, 2023, 62
  • [43] Tezepelumab improves patient-reported outcomes in patients with severe, uncontrolled asthma in PATHWAY
    Corren, Jonathan
    Garcia Gil, Esther
    Griffiths, Janet M.
    Parnes, Jane R.
    van der Merwe, Rene
    Salapa, Kinga
    O'Quinn, Sean
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2021, 126 (02) : 187 - 193
  • [44] EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA GROUPED BY BASELINE BMI IN THE NAVIGATOR STUDY
    Chupp, Geoffrey
    Menzies-Gow, Andrew
    Ambrose, Christopher
    Cook, William
    Kmita, Kamil
    Lindsley, Andrew
    Llanos-Ackert, Jean-Pierre
    Colice, Gene
    Lugogo, Njira
    CHEST, 2021, 160 (04) : 37A - 40A
  • [45] EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA AND HIGH BASELINE BLOOD EOSINOPHIL COUNTS
    Jain, N.
    Llanos-Ackert, J.
    Ambrose, C.
    Cook, B.
    Ponnarambil, S.
    Martin, N.
    Webb, L.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2022, 129 : S36 - S37
  • [46] Benralizumab efficacy in patients with uncontrolled eosinophilic asthma by age at diagnosis
    Wenzel, Sally
    Brusselle, Guy
    Hirsch, Ian
    Zangrilli, James G.
    Rastogi, Sarang
    EUROPEAN RESPIRATORY JOURNAL, 2018, 52
  • [47] TEZEPELUMAB EFFECTS ON INFLAMMATORY BIOMARKERS IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA BY BASELINE BIOMARKER LEVEL
    Lugogo, N.
    Chupp, G.
    Corren, J.
    Israel, E.
    Molfino, N.
    Martin, N.
    Spahn, J.
    Ambrose, C.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2024, 133 (06) : S53 - S54
  • [48] REVIEW OF BIOLOGIC EFFICACY IN PATIENTS WITH UNCONTROLLED ASTHMA BY AGE AT ASTHMA ONSET
    Chipps, B.
    Oppenheimer, J.
    Lugogo, N.
    Mandefro, I.
    Lindsley, A.
    Spahn, J.
    Ambrose, C.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2023, 131 (05) : S52 - S53
  • [49] Efficacy and Safety of Benralizumab for Korean Patients With Severe, Uncontrolled Eosinophilic Asthma
    Park, Hae-Sim
    Lee, Sang Haak
    Lee, Sook Young
    Kim, Mi-Kyeong
    Lee, Byung Jae
    Werkstrom, Viktoria
    Barker, Peter
    Zangrilli, James G.
    ALLERGY ASTHMA & IMMUNOLOGY RESEARCH, 2019, 11 (04) : 508 - 518
  • [50] EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA AND ALLERGIC RHINITIS GROUPED BY BASELINE BLOOD EOSINOPHIL COUNT: POOLED ANALYSIS OF PATHWAY AND NAVIGATOR
    Wechsler, Michael E.
    Chupp, Geoffrey L.
    Israel, Elliot
    Castro, Mario
    Bober, Magdalena
    Lindsley, Andrew
    Spahn, Joe D.
    Ambrose, Christopher S.
    CHEST, 2024, 166 (04) : 4664A - 4680A
12345