Effect of tezepelumab in patients with severe, uncontrolled asthma by age of onset, allergic status, and eosinophilic phenotype

被引：1
|
作者：
Mathur, S. K. [1 ]
Hill, J. L. [2 ,3 ]
Ambrose, C. S. [4 ]
Martin, N. [5 ,6 ,8 ,9 ]
Llanos, J-P [7 ]
Martin, N. [5 ,6 ,8 ,9 ]
Colice, G. [10 ]
机构：
[1] Univ Wisconsin, Dept Med, Div Allergy Pulm & Crit Care Med, Madison, WI USA
[2] San Tan Allergy & Asthma, Arizona Allergy & Immunol Res, Gilbert, AZ USA
[3] Arcadia Allergy & Asthma, Phoenix, AZ USA
[4] AstraZeneca, Resp & Immunol, BioPharmaceut Med, Gaithersburg, MD USA
[5] AstraZeneca, BioPharmaceut RandD, Resp & Immunol, Biometr,Late Stage Dev, Waltham, MA USA
[6] Cytel Inc, Waltham, MA USA
[7] Amgen Inc, Global Med Affairs, Thousand Oaks, CA USA
[8] AstraZeneca, Resp & Immunol, BioPharmaceut Med, Cambridge, England
[9] Univ Leicester, Leicester, Leics, England
[10] AstraZeneca, Late Stage Dev, Resp & Immunol, BioPharmaceut RandD, Gaithersburg, MD USA
来源：
THORAX | 2023年 / 78卷 / SUPPL_4期
关键词：
D O I：
10.1136/thorax-2023-BTSabstracts.125
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
S119
引用
收藏
页码：A86 / A86
页数：1
相关论文
共 50 条
  • [21] Effect of tezepelumab on seasonal exacerbations in patients with severe, uncontrolled asthma grouped by blood eosinophil count
    Corren, J.
    Menzies-Gow, A.
    Ambrose, C. S.
    Colice, G.
    Roseti, S. L.
    Hellqvist, A.
    Kmita, K.
    Lindsley, A. W.
    Cook, B.
    EUROPEAN RESPIRATORY JOURNAL, 2022, 60
  • [22] Severe uncontrolled allergic eosinophilic asthma - looking for the best therapeutic option
    Kuprys-Lipinska, Izabela
    Kuna, Piotr
    ALERGOLOGIA POLSKA-POLISH JOURNAL OF ALLERGOLOGY, 2020, 7 (04) : 180 - 189
  • [23] EFFECT OF TEZEPELUMAB ON LUNG FUNCTION IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA IN THE PHASE 3 NAVIGATOR STUDY
    Israel, Elliot
    Menzies-Gow, Andrew
    Colice, Gene
    Ambrose, Christopher
    Hunter, Gillian
    Cook, William
    Molfino, Nestor
    Llanos-Ackert, Jean-Pierre
    CHEST, 2021, 160 (04) : 41A - 43A
  • [24] Rapid onset of effect of benralizumab in a severe eosinophilic and allergic asthma patient with allergic bronchopulmonary aspergillosis
    Alaga, Arvindran
    Ashraff, Khairil
    Khan, Nurul Hana Din
    RESPIROLOGY CASE REPORTS, 2023, 11 (06):
  • [25] Effect of Tezepelumab on Lung Function in Patients With Severe, Uncontrolled Asthma in the Phase 3 NAVIGATOR Study
    Andrew Menzies-Gow
    Christopher S. Ambrose
    Gene Colice
    Gillian Hunter
    Bill Cook
    Nestor A. Molfino
    Jean-Pierre Llanos
    Elliot Israel
    Advances in Therapy, 2023, 40 : 4957 - 4971
  • [26] Severe, uncontrolled asthma: Tezepelumab targets the airway epithelium
    不详
    ALLERGO JOURNAL, 2024, 33 (08) : 58 - 58
  • [27] Tezepelumab can restore normal lung function in patients with severe, uncontrolled asthma
    Pavord, Ian Douglas
    Brightling, Christopher E.
    Korn, Stephanie
    Martin, Nicole
    Ponnarambil, Sandhia
    Molfino, Nestor A.
    Parnes, Jane R.
    Cook, Bill
    Ambrose, Christopher S.
    EUROPEAN RESPIRATORY JOURNAL, 2023, 62
  • [28] TEZEPELUMAB EFFICACY ACCORDING TO BRONCHODILATOR REVERSIBILITY IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA IN NAVIGATOR
    Menzies-Gow, A.
    Bourdin, A.
    Korn, S.
    Cook, B.
    Ambrose, C.
    Ponnarambil, S.
    Hunter, G.
    Molfino, N.
    Colice, G.
    Llanos-Ackert, J.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2021, 127 (05) : S37 - S37
  • [29] Efficacy of tezepelumab in patients with severe, uncontrolled asthma, according to baseline blood eosinophil count and allergic status: results from the phase 3 NAVIGATOR study
    Menzies-Gow, A.
    Corren, J.
    Cook, B.
    Kmita, K.
    Llanos-Ackert, J.
    Colice, G.
    Ambrose, C. S.
    ALLERGY, 2021, 76 : 21 - 22
  • [30] Tezepelumab Efficacy in Patients with Severe, Uncontrolled Asthma with Comorbid Nasal Polyps in NAVIGATOR 
    Laidlaw, Tanya M.
    Menzies-Gow, Andrew
    Caveney, Scott
    Han, Joseph K.
    Martin, Nicole
    Israel, Elliot
    Lee, Jason K.
    Llanos, Jean-Pierre
    Martin, Neil
    Megally, Ayman
    Parikh, Bhavini
    Vong, Sylvia
    Welte, Tobias
    Corren, Jonathan
    JOURNAL OF ASTHMA AND ALLERGY, 2023, 16 : 915 - 932
12345