Multicomponent Radical Cross-Coupling Reaction of [1.1.1]Propellane: Synthesis of 1-Arylthiol-3-Heteroaryl Bicyclo[1.1.1]pentanes &DAG;

被引：6
|
作者：
Li, Lin [1 ]
Liu, Yumiao [1 ]
Li, Jian [1 ]
Chen, Qing [1 ]
Zhang, Pengfei [1 ]
Shen, Jiabin [1 ,2 ]
Wu, Jirong [1 ]
机构：
[1] Hangzhou Normal Univ, Coll Mat Chem & Chem Engn, Key Lab Organosilicon Chem & Mat Technol, Key Lab Organosilicon Mat Technol,Minist Educ, Hangzhou 311121, Peoples R China
[2] Zhejiang Shuren Univ, Coll Biol & Environm Engn, Key Lab Pollut Exposure & Hlth Intervent Zhejiang, Hangzhou 310015, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2023年 / 365卷 / 18期
基金：
中国国家自然科学基金;
关键词：
Bicyclo[1; 1; 1]pentane; Visible light; Photocatalyst-free; C-H Functionalization; Multi-bond formation; ARYL ACYL PEROXIDES; METAL; QUINOXALIN-2(1H)-ONES; ROUTE; ARYLATION;
D O I：
10.1002/adsc.202300534
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Herein, a visible light-mediated multicomponent radical cross-coupling reaction of [1.1.1]propellane with N-heterocycles and disulfides is described. The mild conditions enabled the installation of the BCP motif in a wide variety of compounds in the absence of photocatalyst, additive and metal catalyst, with excellent functional group tolerance, This methodology opens a approach for the synthesis of potentially bioactive 1-arylthiol-3-heteroaryl bicyclo[1.1.1]pentanes in moderate to good yield.
引用
收藏
页码：3112 / 3117
页数：6
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