Regression of Acoustic Tumor After Chemotherapy for Ovarian Cancer in a Patient With a Breast Cancer Susceptibility Gene 1 (BRCA1) Germline Mutation

被引：2

作者：

Takeda, Anna ^{[1
]}

Kobayashi, Masahito ^{[1
]}

Hasegawa, Kosei ^{[2
]}

Fujimaki, Takamitsu ^{[1
]}

机构：

[1] Saitama Med Univ Hosp, Neurosurg, Saitama, Japan

[2] Saitama Med Univ, Int Med Ctr, Gynecol Oncol, Saitama, Japan

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 03期

关键词：

brca1; breast cancer susceptibility gene; acoustic tumor; olaparib; brca1 germline mutation; ovarian cancer; case report; vestibular schwannoma; RISK;

D O I：

10.7759/cureus.35917

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report the case of an adult woman who developed ovarian cancer during a follow-up for vestibular schwannoma. Volume reduction of the schwannoma was observed after chemotherapy for ovarian cancer. After ovarian cancer had been diagnosed, the patient was found to have a germline mutation of breast cancer susceptibility gene 1 (BRCA1). This is the first reported case of vestibular schwannoma in a patient with a germline mutation of BRCA1 and the first documented example of chemotherapy including olaparib to have shown efficacy for schwannoma.

引用

页数：4

共 13 条

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