Regression of Acoustic Tumor After Chemotherapy for Ovarian Cancer in a Patient With a Breast Cancer Susceptibility Gene 1 (BRCA1) Germline Mutation

被引：2
作者：
Takeda, Anna [1 ]
Kobayashi, Masahito [1 ]
Hasegawa, Kosei [2 ]
Fujimaki, Takamitsu [1 ]
机构：
[1] Saitama Med Univ Hosp, Neurosurg, Saitama, Japan
[2] Saitama Med Univ, Int Med Ctr, Gynecol Oncol, Saitama, Japan
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 03期
关键词：
brca1; breast cancer susceptibility gene; acoustic tumor; olaparib; brca1 germline mutation; ovarian cancer; case report; vestibular schwannoma; RISK;
D O I：
10.7759/cureus.35917
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report the case of an adult woman who developed ovarian cancer during a follow-up for vestibular schwannoma. Volume reduction of the schwannoma was observed after chemotherapy for ovarian cancer. After ovarian cancer had been diagnosed, the patient was found to have a germline mutation of breast cancer susceptibility gene 1 (BRCA1). This is the first reported case of vestibular schwannoma in a patient with a germline mutation of BRCA1 and the first documented example of chemotherapy including olaparib to have shown efficacy for schwannoma.
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页数：4
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