Studies on the role of non-coding RNAs in controlling the activity of T cells in asthma

被引:7
作者
Sufianov, Albert [1 ,2 ]
Bessonova, Marina [3 ]
Begliarzade, Sema [4 ]
Kudriashov, Valentin [5 ]
Danilov, Andrei [6 ]
Ilyasova, Tatiana [7 ]
Yaolou, Wang [8 ]
Nafikova, Radmila [9 ]
Beylerli, Ozal [1 ,10 ]
机构
[1] Peoples Friendship Univ Russia, RUDN Univ, Educ & Sci Inst Neurosurg, Moscow, Russia
[2] Sechenov First Moscow State Med Univ, Sechenov Univ, Dept Neurosurg, Moscow, Russia
[3] Russian Acad Sci, Tyumen Cardiol Res Ctr, Tomsk Natl Res Med Ctr, Tomsk, Russia
[4] Republican Clin Perinatal Ctr, Ufa 450106, Russia
[5] Sichuan Univ, West China Hosp, Gastr Canc Ctr, Chengdu, Peoples R China
[6] Smolensk State Med Univ, Dept Clin Pharmacol, Smolensk, Russia
[7] Bashkir State Med Univ, Dept Internal Dis, Ufa 450008, Russia
[8] Harbin Med Univ, 157 Baojian Rd, Harbin 150088, Heilongjiang, Peoples R China
[9] Northwestern Univ, Dept Pulm & Crit care, Chicago, IL USA
[10] Peoples Friendship Univ Russia, RUDN Univ, 6 Miklukho-Maklaya St, Moscow 117198, Russia
来源
NON-CODING RNA RESEARCH | 2023年 / 8卷 / 02期
关键词
Non-coding RNAs; Circular RNAs; Long non-coding RNAs; microRNAs; Asthma; T cells; AIRWAY INFLAMMATION; MEDIATED REGULATION; MICRORNA REGULATION; CIRCULAR RNAS; EXPRESSION; BALANCE; DIFFERENTIATION; ANTAGONISM; RESPONSES; TH1/TH2;
D O I
10.1016/j.ncrna.2023.02.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Bronchial asthma, commonly known as asthma, is a chronic inflammatory disease characterized by airway inflammation, increased responsiveness and changes in airway structure. T cells, particularly T helper cells, play a crucial role in the disease. Non-coding RNAs, which are RNAs that do not code for proteins, mainly include microRNAs, long non-coding RNAs, and circular RNAs, play a role in regulating various biological processes. Studies have shown that non-coding RNAs have an important role in the activation and transformation of T cells and other biological processes in asthma. The specific mechanisms and clinical applications are worth further examination. This article reviews the recent research on the role of microRNAs, long non-coding RNAs and circular RNAs in T cells in asthma.
引用
收藏
页码:211 / 217
页数:7
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