Synthesis of isochromanone containing natural products from myxobacteria

被引:6
作者
Salimimarand, Mina [1 ]
Rizzacasa, Mark A. [1 ]
机构
[1] Univ Melbourne, Mol Sci & Biotechnol Inst Bio21, Sch Chem, Parkville, Vic 3010, Australia
关键词
AJUDAZOL-A; CHONDROMYCES-CROCATUS; DISCOVERY; 8-DESHYDROXYAJUDAZOL; NORICUMAZOLE; ANTIBIOTICS; ASSIGNMENT; TUBULYSINS; INHIBITORS; MECHANISM;
D O I
10.1039/d2ob01926d
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
This review details the biological activity, biosynthesis and synthesis of isochromanone metabolites isolated from myxobacteria. Strategies towards the synthesis of the isochomanone and oxazole fragments of these natural products are highlighted.
引用
收藏
页码:1341 / 1355
页数:15
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