Intravascular Imaging in Patients With Complex Coronary Lesions and Chronic Kidney Disease

被引:6
作者
Kwon, Woochan [1 ]
Choi, Ki Hong [1 ]
Song, Young Bin [1 ]
Park, Yong Hwan [2 ]
Lee, Joo Myung [1 ]
Lee, Jong-Young [3 ]
Lee, Seung-Jae [3 ]
Lee, Sang Yeub [4 ,5 ]
Kim, Sang Min [4 ]
Yun, Kyeong Ho [6 ]
Cho, Jae Young [6 ]
Kim, Chan Joon [7 ]
Ahn, Hyo-Suk [7 ]
Nam, Chang-Wook [8 ]
Yoon, Hyuck-Jun [8 ]
Lee, Wang Soo [9 ]
Jeong, Jin-Ok [10 ]
Song, Pil Sang [10 ]
Doh, Joon-Hyung [11 ]
Jo, Sang-Ho [12 ]
Yoon, Chang-Hwan [13 ]
Hong, David [1 ]
Park, Taek Kyu [1 ]
Yang, Jeong Hoon [1 ]
Choi, Seung-Hyuk [1 ]
Gwon, Hyeon-Cheol [1 ]
Hahn, Joo-Yong [1 ]
机构
[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Seoul, South Korea
[2] Sungkyunkwan Univ, Samsung Changwon Hosp, Sch Med, Chang Won, South Korea
[3] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Seoul, South Korea
[4] Chungbuk Natl Univ, Chungbuk Natl Univ Hosp, Coll Med, Cheongju, South Korea
[5] Chung Ang Univ, Coll Med, Gwangmyeong Hosp, Gwangmyeong, South Korea
[6] Wonkwang Univ Hosp, Iksan, South Korea
[7] Catholic Univ Korea, Uijeongbu St Marys Hosp, Seoul, South Korea
[8] Keimyung Univ, Dongsan Hosp, Daegu, South Korea
[9] Chung Ang Univ, Chung Ang Univ Hosp, Coll Med, Seoul, South Korea
[10] Chungnam Natl Univ, Chungnam Natl Univ Hosp, Coll Med, Daejeon, South Korea
[11] Inje Univ, Ilsan Paik Hosp, Goyang, South Korea
[12] Hallym Univ, Sacred Heart Hosp, Cardiovasc Ctr, Anyang, South Korea
[13] Seoul Natl Univ, Bundang Hosp, Seongnam Si, Gyeonggi Do, South Korea
关键词
ELUTING STENT IMPLANTATION; CLINICAL-OUTCOMES; ANGIOGRAPHY; ULTRASOUND;
D O I
10.1001/jamanetworkopen.2023.45554
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
IMPORTANCE As patients with chronic kidney disease (CKD) are more likely to have complex coronary lesions, intravascular imaging guidance in percutaneous coronary intervention (PCI) for this population could be potentially beneficial. OBJECTIVES To investigate whether the outcomes of intravascular imaging-guided procedural optimization would be different according to the presence of CKD. DESIGN, SETTING, AND PARTICIPANTS This was a prespecified substudy of RENOVATE-COMPLEX-PCI, a recently published multicenter randomized clinical trial in Korea studying the benefits of intravascular imaging for complex coronary lesions. Patients with complex coronary lesions, with or without CKD, were enrolled between May 2018 and May 2021. Data were analyzed from January to June 2023. INTERVENTIONS PCI in each group was done either under the guidance of intravascular imaging or angiography alone. MAIN OUTCOMES AND MEASURES The primary end point was target vessel failure (TVF) at the 3-year point, defined as a composite of cardiac death, target vessel-related myocardial infarction, or clinically driven target vessel revascularization. RESULTS A total of 1639 patients (1300 male [79.3%]) treated with PCI for complex coronary lesions were stratified into CKD (296 participants) and non-CKD (1343 participants) groups. The mean (SD) age of each group was 70.3 (9.4) and 64.5 (10.1) years, and mean (SD) estimated serum creatinine was 2.9 (5.3) and 0.8 (0.2) mg/dL for CKD and non-CKD groups, respectively. Intravascular imaging-guided revascularization was associated with significantly lower incidence of the primary end point compared with angiography-guided revascularization in both CKD (13.3% vs 23.3%; hazard ratio [HR], 0.51; 95% CI, 0.27-0.93; P =.03) and non-CKD (6.4% vs 9.9%; HR, 0.66; 95% CI, 0.44-0.99; P =.05) groups. The significantly lower incidence of the primary end point was mainly associated with the lower risk of cardiac death or target vessel-related myocardial infarction (9.4% vs 22.2%; HR, 0.39; 95% CI, 0.20-0.76; P =.006) in the CKD group and by target vessel revascularization (3.0% vs 5.5%; HR, 0.55; 95% CI, 0.30-0.99; P =.05) in the non-CKD group. Those with a glomerular filtration rate of at least 30 mL/min/1.73m(2) and less than 60 ml/kg/1.73m(2) showed the greatest benefit from imaging-guided complex PCI (8.8% vs 21.2%; HR, 0.28; 95% CI, 0.11-0.68; P =.02). CONCLUSIONS AND RELEVANCE In this prespecified cohort substudy of the Randomized Controlled Trial of Intravascular Imaging Guidance versus Angiography-Guidance on Clinical Outcomes After Complex Percutaneous Coronary Intervention trial, intravascular imaging guidance showed clinical benefit over angiography guidance in reducing the risk of TVF, regardless of the presence of CKD. The greatest benefits of imaging-guided complex PCI were observed in stage 3 CKD. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT03381872
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页数:13
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[41]   Role of Intravascular Imaging for the Diagnosis of Recanalized Coronary Thrombus [J].
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[49]   Clinical and Therapeutic Characteristics in Patients with Chronic Kidney Disease presenting with Acute Coronary Syndrome [J].
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[50]   Prevalence of chronic kidney disease among patients undergoing transradial percutaneous coronary interventions [J].
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Patel, Tejas ;
Gandhi, Bhavika ;
Patel, Shrinil ;
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Costanzo, Eric J. ;
Cosentino, James ;
Patel, Chirag ;
Dewan, Asa ;
Kuo, Yen-Hong ;
Salman, Loay ;
Vachharajani, Tushar J. .
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