MiRNAs in Lung Adenocarcinoma: Role, Diagnosis, Prognosis, and Therapy

被引：25
作者：
Song, Yongan [1 ]
Kelava, Leonardo [2 ]
Kiss, Istvan [1 ]
机构：
[1] Univ Pecs, Med Sch, Dept Publ Hlth Med, Szigeti Str 12, H-7624 Pecs, Hungary
[2] Univ Pecs, Inst Translat Med, Med Sch, Dept Thermophysiol, Sziget Str 12, H-7624 Pecs, Hungary
来源：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2023年 / 24卷 / 17期
基金：
英国科研创新办公室;
关键词：
miRNA; LUAD; tumor suppressor; oncogenic; diagnosis; prognosis; therapy; FACTOR RECEPTOR MUTATIONS; SQUAMOUS-CELL CARCINOMA; MICRORNA EXPRESSION; TUMOR-GROWTH; SIGNALING PATHWAY; NUCLEAR EXPORT; CANCER; PROMOTES; METASTASIS; BIOMARKERS;
D O I：
10.3390/ijms241713302
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Lung cancer has emerged as a significant public health challenge and remains the leading cause of cancer-related mortality worldwide. Among various types of lung malignancies, lung adenocarcinoma (LUAD) stands as the most prevalent form. MicroRNAs (miRNAs) play a crucial role in gene regulation, and their involvement in cancer has been extensively explored. While several reviews have been published on miRNAs and lung cancer, there remains a gap in the review regarding miRNAs specifically in LUAD. In this review, we not only highlight the potential diagnostic, prognostic, and therapeutic implications of miRNAs in LUAD, but also present an inclusive overview of the extensive research conducted on miRNAs in this particular context.
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页数：25
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