Effect of High Body Mass Index on Survivorship After Lateral Meniscal Allograft Transplantation: A Propensity Score Matching Analysis

Background:Preoperative body mass index (BMI) is one of the correctable factors before surgery. Few studies have investigated the effect of BMI on the survivorship of lateral meniscal allograft transplantation (MAT). Hypothesis:Patients with a high BMI have inferior survivorship after lateral MAT when compared with those with a normal BMI. Study Design:Cohort study; Level of evidence, 3. Methods:Overall, 306 consecutive patients who underwent lateral MAT were retrospectively reviewed. According to the classification criteria of the World Health Organization, patients were split into 2 groups: normal weight (BMI <25.0) and overweight (BMI & GE;25.0). There were 104 patients (34.0%) allocated into the overweight group. Given the demographic heterogeneity between the groups, propensity score matching was performed. Before and after propensity score matching, the anatomic and clinical survival rates of the 2 groups were compared by Kaplan-Meier survival analysis. Anatomic failure was defined as a tear covering >50% of the allograft or unstable peripheral rim on follow-up magnetic resonance imaging and second-look arthroscopy. Clinical failure was defined as a Lysholm score <65 or need for additional surgery, such as revision MAT. Results:For all patients, the mean & PLUSMN; SD follow-up period was 6.9 & PLUSMN; 4.2 years. The mean BMI of the overweight and normal weight groups was 27.8 & PLUSMN; 2.6 and 22.0 & PLUSMN; 1.9, respectively. The mean Lysholm scores at the last follow-up were not significantly different between the groups. However, the anatomic survival rate in the overweight group (77.9%) was significantly lower than that in the normal weight group (90.1%) (P < .001). The clinical survival rate (82.7%) in the overweight group was significantly lower than that in the normal weight group (95.0%) (P < .001). After propensity score matching for patient characteristics, which left 87 patients per group, the anatomic and clinical survival rates were significantly lower in the overweight group. Conclusion:Preoperative high BMI was associated with inferior anatomic and clinical survival rates. The results of the current study suggest that weight loss before lateral MAT may be required in overweight patients for the improvement of anatomic and clinical survival rates.