Anti-Mi-2 antibody-positive lung cancer-associated polymyositis

被引：0

作者：

Shimoda, Masafumi ^{[1
]}

Tanaka, Yoshiaki ^{[1
]}

Taniguchi, Atsuo ^{[2
]}

Morimoto, Kozo ^{[1
]}

Yoshimori, Kozo ^{[1
]}

Ohta, Ken ^{[1
]}

机构：

[1] Fukujuji Hosp, Resp Dis Ctr, Japan AntiTB Assoc, 3-1-24 Mastuyama, Kiyose, Tokyo 2048522, Japan

[2] Fukujuji Hosp, Dept Rheumatol, Japan AntiTB Assoc, Kiyose, Tokyo, Japan

来源：

INTERNATIONAL CANCER CONFERENCE JOURNAL | 2023年 / 12卷 / 03期

关键词：

Lung cancer; Polymyositis; Anti-Mi-2; antibody; Creatinine kinase; Cancer-associated myositis; DERMATOMYOSITIS; AUTOANTIBODIES; MYOSITIS; DISEASE;

D O I：

10.1007/s13691-023-00601-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

After a 75-year-old man was diagnosed with lung cancer, proximal weakness and myalgia in the bilateral lower extremities developed, and the creatinine kinase (CK) level was elevated. The anti-Mi-2 antibody test was positive, muscle T2-weighted/fat-suppressed magnetic resonance imaging showed high intensity, and there were no skin lesions. Therefore, he was diagnosed with lung cancer-associated polymyositis (PM). The lung tumour shrank after chemotherapy, accompanied by gradual improvement of his PM-derived symptoms and CK level. Although positive anti-Mi-2 antibody tests rarely indicate PM and cancer, examining myositis-specific autoantibodies, including anti-Mi-2, should be considered if the CK level increases after a cancer diagnosis.

引用

页码：173 / 176

页数：4

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