Impact and predictors of device-related thrombus after percutaneous left atrial appendage closure

被引：6
作者：
Branca, Luca [1 ]
Tomasoni, Daniela [1 ]
Cimino, Giuliana [1 ]
Cersosimo, Angelica [1 ]
Lombardi, Carlo Mario [1 ]
Chizzola, Giuliano [1 ]
Metra, Marco [1 ]
Adamo, Marianna [1 ,2 ]
机构：
[1] Univ Brescia, Dept Med & Surg Specialties, Cardiac Catheterizat Lab & Cardiol, ASST Spedali Civili Brescia,Radiol Sci & Publ Hlth, Brescia, Italy
[2] Piazzale Spedali Civili 1, I-25123 Brescia, Italy
来源：
JOURNAL OF CARDIOVASCULAR MEDICINE | 2023年 / 24卷 / 01期
关键词：
atrial fibrillation; device-related thrombus; left atrial appendage closure; AMPLATZER CARDIAC PLUG; ORAL ANTICOAGULATION; WATCHMAN DEVICE; FIBRILLATION; WARFARIN; OCCLUSION; CONTRAINDICATION; EFFICACY; THERAPY; SAFETY;
D O I：
10.2459/JCM.0000000000001394
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Device-related thrombus (DRT) is a known complication occurring in up to 7% of patients undergoing percutaneous left atrial appendage closure (LAAC). Since the target population of LAAC is generally ineligible for oral anticoagulant therapies, DRT raises important concerns. The aim of this review will be to summarize available evidence on DRT after LAAC focusing on its possible impact on outcomes. Recent findings showed a tighter association between DRT and neurological ischemic events. Antithrombotic regimen adopted after LAAC may have a protective effect against DRT. Many patient-related and procedural factors have been identified as possible predictors of DRT. A tailored approach, which takes into account DRT, is needed in the patient selection for LAAC and in the postprocedural follow-up.
引用
收藏
页码：12 / 19
页数：8
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