The latest advances in the pharmacological management of endometriosis

被引:4
作者
Hartner, Gabriel [1 ]
Husslein, Heinrich [1 ]
Kuessel, Lorenz [1 ]
Gstoettner, Manuela [1 ]
Tiringer, Denise [1 ]
Wenzl, Rene [1 ]
Perricos, Alexandra [1 ]
机构
[1] Med Univ Vienna, Dept Obstet & Gynecol, Waehringer Guertel 18-20, A-1090 Vienna, Austria
关键词
Endometriosis; GnRH antagonists; immunomodulators; pharmacological treatment; aromatase inhibitors; SPRMs; SERMs; CHRONIC PELVIC PAIN; ESTROGEN-RECEPTOR MODULATOR; CAUSES REGRESSION; DOUBLE-BLIND; METFORMIN; SIMVASTATIN; AROMATASE; EXPRESSION; EFFICACY; THERAPY;
D O I
10.1080/14656566.2022.2045274
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Introduction Endometriosis is a benign disease, characterized by a wide range of symptoms and different degrees of severity, which is why therapy should be individually adapted to the patient's needs. Over the years, a lot of research has gone into finding new therapeutic approaches for this enigmatic disease. Areas covered This review presents the latest advances in pharmacological management of endometriosis and is solely focused on studies published from 2010 to 2021 Expert opinion Clinicians and researchers are constantly searching for new therapeutic strategies for endometriosis patients. As there are well-established treatments, however, any new medication should fulfill at least one of the three criteria: increased efficacy, comparable efficacy but a better safety profile, or treatments that have a lack of accompanying contraceptive effects that are seen in most endometriosis treatments. While some new substances show promising results, further studies are needed to demonstrate the fulfillment of one of the above-mentioned criteria.
引用
收藏
页码:121 / 133
页数:13
相关论文
共 50 条
  • [21] Current Strategies for Endometriosis Management
    Kodaman, Pinar H.
    OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA, 2015, 42 (01) : 87 - +
  • [22] A review of phase II and III drugs for the treatment and management of endometriosis
    Perrone, Umberto
    Evangelisti, Giulio
    Lagana, Antonio Simone
    Bogliolo, Stefano
    Ceccaroni, Marcello
    Izzotti, Alberto
    Gustavino, Claudio
    Ferrero, Simone
    Barra, Fabio
    EXPERT OPINION ON EMERGING DRUGS, 2023, : 333 - 351
  • [23] Recent Advances in the Pharmacological Management of Atrial Fibrillation
    Gooden, Janelle Y.
    Powell, Brian D.
    Akogyeram, Clement O.
    Melduni, Rowlens M.
    AMERICAN JOURNAL OF THERAPEUTICS, 2016, 23 (01) : E118 - E138
  • [24] Endometriosis A Review on New Advances in Clinical Diagnosis and Management
    Alshebly, Mashael Marzouq
    JOURNAL OF REPRODUCTIVE MEDICINE, 2019, 64 (7-8) : 270 - 274
  • [25] Advances in Treatment Options of Endometriosis
    Oezkan, Sebiha
    Arici, Aydin
    GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2009, 67 (02) : 81 - 91
  • [26] Novel pharmacological therapies for the treatment of endometriosis
    Buggio, Laura
    Dridi, Dhouha
    Barbara, Giussy
    Merli, Camilla E. M.
    Cetera, Giulia Emily
    Vercellini, Paolo
    EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 2022, 15 (09) : 1039 - 1052
  • [27] ESHRE guideline: management of women with endometriosis
    Dunselman, G. A. J.
    Vermeulen, N.
    Becker, C.
    Calhaz-Jorge, C.
    D'Hooghe, T.
    De Bie, B.
    Heikinheimo, O.
    Horne, A. W.
    Kiesel, L.
    Nap, A.
    Prentice, A.
    Saridogan, E.
    Soriano, D.
    Nelen, W.
    HUMAN REPRODUCTION, 2014, 29 (03) : 400 - 412
  • [28] Cutting-Edge Approaches to Obesity Management: The Latest Pharmacological Options
    Schmitz, Sarah H.
    Saunders, Katherine H.
    Aronne, Louis J.
    ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 2025, 54 (01) : 85 - 102
  • [29] Management of pelvic pain caused by endometriosis
    Balalau, Oana Denisa
    Ciupitu, Ioana Andreea
    Bogheanu, Delia-Maria
    Ghiocel-Zariosu, Alexia-Ioana
    Balalau, Cristian
    Ples, Liana
    Balan, Daniela Gabriela
    Paunica, Ioana
    Sima, Romina Marina
    JOURNAL OF MIND AND MEDICAL SCIENCES, 2023, 10 (01): : 79 - 84
  • [30] A Review of Recent Pharmacological Advances in the Management of Diabetes-Associated Peripheral Neuropathy
    Syed, Osman
    Jancic, Predrag
    Knezevic, Nebojsa Nick
    PHARMACEUTICALS, 2023, 16 (06)