Synthetic Methods for Various Chromeno-fused Heterocycles and their Potential as Antimicrobial Agents

被引：7

作者：

Agrawal, Neetu ^{[1
]}

Goswami, Radhika ^{[1
]}

Pathak, Shilpi ^{[1
]}

机构：

[1] GLA Univ, Inst Pharmaceut Res, Mathura 281406, UP, India

来源：

MEDICINAL CHEMISTRY | 2024年 / 20卷 / 02期

关键词：

Chromene; antimicrobial; synthesis; heterocycle; therapeutic agent; fused compounds; EFFICIENT SYNTHESIS; ANTIBACTERIAL ACTIVITY; DERIVATIVES;

D O I：

10.2174/0115734064274748231005074100

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Chromenes are a significant family of heterocyclic chemicals that have a wide range of biological applications, a simple chemical structure, and only mildly undesirable side effects. The synthesis of a wide range of chromene analogs that displayed unexpected behaviors via numerous mechanisms was investigated by a number of different research teams, which led to the discovery of multiple pathways for their synthesis. In addition, different chromene-fused heterocycles exhibit a wide variety of fascinating biological actions, including those that are anticancer, anticonvulsant, antibacterial, anticholinesterase, antituberculosis, and anti-diabetic. In light of this, the purpose of this study is to highlight the many synthesis techniques and antibacterial activity associated with chromene-fused heterocyclic compounds. Moreover, such research can open avenues for exploring other therapeutic applications of these compounds in various disease areas, as their biological activities extend beyond antibacterial effects.

引用

页码：115 / 129

页数：15

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