Multifunctional hydrogel bioscaffolds based on polysaccharide to promote wound healing: A review

被引：12

作者：

Ding, Chuanbo ^{[1
]}

Liu, Xinglong ^{[1
]}

Zhang, Shuai ^{[2
]}

Sun, Shuwen ^{[2
]}

Yang, Jiali ^{[2
]}

Chai, Guodong ^{[2
]}

Wang, Ning ^{[2
]}

Ma, Shuang ^{[2
]}

Ding, Qiteng ^{[2
,3
]}

Liu, Wencong ^{[4
]}

机构：

[1] Jilin Agr Sci & Technol Coll, Coll Tradit Chinese Med, Jilin 132101, Peoples R China

[2] Jilin Agr Univ, Changchun 130118, Peoples R China

[3] Sci & Technol Innovat Ctr Hlth Prod & Med Mat Char, Changchun 130118, Peoples R China

[4] Wuzhou Univ, Sch Food & Pharmaceut Engn, Wuzhou 543002, Peoples R China

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2024年 / 259卷

关键词：

Hydrogel; Bioengineering scaffold; Wound healing; TEMPORAL STABILITY; OXIDATIVE STRESS; IN-VITRO; ANTIBACTERIAL; ANTIOXIDANT; CHITOSAN; CURCUMIN; TRAUMA; OXYGEN; RATS;

D O I：

10.1016/j.ijbiomac.2024.129356

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Various types of skin wounds pose challenges in terms of healing and susceptibility to infection, which can have a significant impact on physical and mental well-being, and in severe cases, may result in amputation. Conventional wound dressings often fail to provide optimal support for these wounds, thereby impeding the healing process. As a result, there has been considerable interest in the development of multifunctional polymer matrix hydrogel scaffolds for wound healing. This review offers a comprehensive review of the characteristics of polysaccharide-based hydrogel scaffolds, as well as their applications in different types of wounds. Additionally, it evaluates the advantages and disadvantages associated with various types of multifunctional polymer and polysaccharide-based hydrogel scaffolds. The objective is to provide a theoretical foundation for the utilization of multifunctional hydrogel scaffolds in promoting wound healing.

引用

页数：11