Multifunctional hydrogel bioscaffolds based on polysaccharide to promote wound healing: A review

被引:20
作者
Ding, Chuanbo [1 ]
Liu, Xinglong [1 ]
Zhang, Shuai [2 ]
Sun, Shuwen [2 ]
Yang, Jiali [2 ]
Chai, Guodong [2 ]
Wang, Ning [2 ]
Ma, Shuang [2 ]
Ding, Qiteng [2 ,3 ]
Liu, Wencong [4 ]
机构
[1] Jilin Agr Sci & Technol Coll, Coll Tradit Chinese Med, Jilin 132101, Peoples R China
[2] Jilin Agr Univ, Changchun 130118, Peoples R China
[3] Sci & Technol Innovat Ctr Hlth Prod & Med Mat Char, Changchun 130118, Peoples R China
[4] Wuzhou Univ, Sch Food & Pharmaceut Engn, Wuzhou 543002, Peoples R China
关键词
Hydrogel; Bioengineering scaffold; Wound healing; TEMPORAL STABILITY; OXIDATIVE STRESS; IN-VITRO; ANTIBACTERIAL; ANTIOXIDANT; CHITOSAN; CURCUMIN; TRAUMA; OXYGEN; RATS;
D O I
10.1016/j.ijbiomac.2024.129356
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Various types of skin wounds pose challenges in terms of healing and susceptibility to infection, which can have a significant impact on physical and mental well-being, and in severe cases, may result in amputation. Conventional wound dressings often fail to provide optimal support for these wounds, thereby impeding the healing process. As a result, there has been considerable interest in the development of multifunctional polymer matrix hydrogel scaffolds for wound healing. This review offers a comprehensive review of the characteristics of polysaccharide-based hydrogel scaffolds, as well as their applications in different types of wounds. Additionally, it evaluates the advantages and disadvantages associated with various types of multifunctional polymer and polysaccharide-based hydrogel scaffolds. The objective is to provide a theoretical foundation for the utilization of multifunctional hydrogel scaffolds in promoting wound healing.
引用
收藏
页数:11
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