Endothelial Function in Dyslipidemia: Roles of LDL-Cholesterol, HDL-Cholesterol and Triglycerides

被引：29

作者：

Higashi, Yukihito ^{[1
,2
]}

机构：

[1] Hiroshima Univ, Res Inst Radiat Biol & Med, Dept Regenerat Med, Hiroshima 7438551, Japan

[2] Hiroshima Univ Hosp, Med Ctr Translat & Clin Res, Div Regenerat & Med, Hiroshima 7348553, Japan

来源：

CELLS | 2023年 / 12卷 / 09期

关键词：

endothelial function; dyslipidemia; low-density lipoprotein cholesterol; high-density lipoprotein cholesterol; triglycerides; HIGH-DENSITY-LIPOPROTEIN; CORONARY-HEART-DISEASE; FOAM CELL-FORMATION; NITRIC-OXIDE; DEPENDENT VASODILATION; OXIDATIVE STRESS; RISK-FACTORS; MATERNAL HYPERCHOLESTEROLEMIA; CARDIOVASCULAR-DISEASE; SERUM TRIGLYCERIDES;

D O I：

10.3390/cells12091293

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Dyslipidemia is associated with endothelial dysfunction. Endothelial dysfunction is the initial step for atherosclerosis, resulting in cardiovascular complications. It is clinically important to break the process of endothelial dysfunction to cardiovascular complications in patients with dyslipidemia. Lipid-lowering therapy enables the improvement of endothelial function in patients with dyslipidemia. It is likely that the relationships of components of a lipid profile such as low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides with endothelial function are not simple. In this review, we focus on the roles of components of a lipid profile in endothelial function.

引用

页数：15

共 50 条

[21] Low HDL-cholesterol in persons with normal LDL-cholesterol is associated with an increased risk of stroke
Suri, MFK
Zhou, JY
Qureshi, AI
NEUROLOGY, 2006, 66 (05) : A221 - A221
[22] THE EFFECT OF APOLIPOPROTEIN-E ISOFORM DIFFERENCE ON POSTPRANDIAL LIPOPROTEIN COMPOSITION IN PATIENTS MATCHED FOR TRIGLYCERIDES, LDL-CHOLESTEROL, AND HDL-CHOLESTEROL
SUPERKO, HR
HASKELL, WL
ARTERY, 1991, 18 (06) : 315 - 325
[23] HDL-cholesterol particles inhibit endoplasmic reticulum stress induced by LDL-cholesterol oxides
Favre, D.
Niederhaeuser, G.
Waeber, G.
Abderrahmani, A.
DIABETES & METABOLISM, 2008, 34 : A37 - A37
[24] The alterations of cholesterol, HDL-cholesterol and LDL-cholesterol in Chinese with hepatocellular carcinoma: A cross-sectional study
Zhang, Junguo
Cao, Xiue
Liu, Bin
Luan, Fang
ASIAN JOURNAL OF SURGERY, 2019, 42 (10) : 938 - 939
[25] TOTAL CHOLESTEROL, HDL-CHOLESTEROL AND LDL-CHOLESTEROL IN RAT SERUM - ESTIMATED WITH DIFFERENT METHODS IN COMPARISON TO THE ULTRACENTRIFUGATION
ELMADFA, I
NIEBUHR, S
SCHMITT, B
FETTE SEIFEN ANSTRICHMITTEL, 1986, 88 (08): : 316 - 320
[26] Evaluation of calculated LDL-cholesterol when cholesterol, triglycerides and HDL-cholesterol are measured on the Dimension RxL analyzer as against the Cobas Integra 700 analyzer.
Ng, S
Lim, B
Ramli, A
Wee, C
Tay, B
Sethi, S
CLINICAL CHEMISTRY, 2003, 49 (06) : A165 - A165
[27] Assessment of current National Cholesterol Education Program guidelines for total cholesterol, triglyceride, HDL-cholesterol, and LDL-cholesterol measurements
Caudill, SP
Cooper, GR
Smith, SJ
Myers, GL
CLINICAL CHEMISTRY, 1998, 44 (08) : 1650 - 1658
[28] Coronary heart disease in patients with low LDL-cholesterol - Benefit of pravastatin in diabetics and enhanced role for HDL-cholesterol and triglycerides as risk factors
Sacks, FM
Tonkin, AM
Craven, T
Pfeffer, MA
Shepherd, J
Keech, A
Furberg, CD
Braunwald, E
CIRCULATION, 2002, 105 (12) : 1424 - 1428
[29] Correlations between LDL-cholesterol, non HDL-cholesterol and aplipoprotein B in mixed dyslipidemia and lipid-lowering effect of various treatments
Farnier, M.
Hannachi, H.
Dong, Q.
Shah, A.
Brudi, P.
DIABETES & METABOLISM, 2010, 36 : A94 - A94
[30] HDL-CHOLESTEROL AND LDL-CHOLESTEROL IN NORMAL WEIGHT HEALTHY-CHILDREN 13 YEARS OF AGE
WIDHALM, K
STROBL, W
EUROPEAN JOURNAL OF PEDIATRICS, 1979, 132 (02) : 125 - 130

← 1 2 3 4 5 →