Endothelial Function in Dyslipidemia: Roles of LDL-Cholesterol, HDL-Cholesterol and Triglycerides

被引：52

作者：

Higashi, Yukihito ^{[1
,2
]}

机构：

[1] Hiroshima Univ, Res Inst Radiat Biol & Med, Dept Regenerat Med, Hiroshima 7438551, Japan

[2] Hiroshima Univ Hosp, Med Ctr Translat & Clin Res, Div Regenerat & Med, Hiroshima 7348553, Japan

来源：

CELLS | 2023年 / 12卷 / 09期

关键词：

endothelial function; dyslipidemia; low-density lipoprotein cholesterol; high-density lipoprotein cholesterol; triglycerides; HIGH-DENSITY-LIPOPROTEIN; CORONARY-HEART-DISEASE; FOAM CELL-FORMATION; NITRIC-OXIDE; DEPENDENT VASODILATION; OXIDATIVE STRESS; RISK-FACTORS; MATERNAL HYPERCHOLESTEROLEMIA; CARDIOVASCULAR-DISEASE; SERUM TRIGLYCERIDES;

D O I：

10.3390/cells12091293

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Dyslipidemia is associated with endothelial dysfunction. Endothelial dysfunction is the initial step for atherosclerosis, resulting in cardiovascular complications. It is clinically important to break the process of endothelial dysfunction to cardiovascular complications in patients with dyslipidemia. Lipid-lowering therapy enables the improvement of endothelial function in patients with dyslipidemia. It is likely that the relationships of components of a lipid profile such as low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides with endothelial function are not simple. In this review, we focus on the roles of components of a lipid profile in endothelial function.

引用

页数：15

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