Simple One-Pot Synthesis of Novel 5-(3,5-Dialkyl-1H-pyrazol-1-yl)-2-ethoxy-1,4,2λ5-diazaphosphole 2-Oxides

被引：1
作者：
Assiri, M. A. [1 ]
Ali, T. E. [1 ,2 ]
Alzahrani, A. Y. [3 ]
Salem, M. A. [3 ,4 ]
机构：
[1] King Khalid Univ, Fac Sci, Dept Chem, Abha 61421, Saudi Arabia
[2] Ain Shams Univ, Fac Educ, Dept Chem, Cairo 11711, Egypt
[3] King Khalid Univ, Fac Sci & Arts, Dept Chem, Mohail 61435, Saudi Arabia
[4] Al Azhar Univ, Fac Sci, Dept Chem, Cairo 11884, Egypt
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 59卷 / 02期
关键词：
synthesis; one-pot reaction; pyrazole; 1; 4; 2-diazaphosphole; DERIVATIVES;
D O I：
10.1134/S1070428023020094
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple one-pot synthesis of novel 5-pyrazolyl-1,4,2-diazaphosphole derivatives is developed. The synthesis involves a three-component reaction of dimethyl (formamide/acetamide) dimethyl acetal or carbon disulfide with triethyl phosphite and 1H-pyrazole-1-carboximidamides in dioxane. The structure of the synthesized compounds was confirmed by spectral methods and elemental analysis.
引用
收藏
页码：285 / 289
页数：5
相关论文
共 25 条
[1]   Facile regioselective synthesis and antimicrobial activity of heterocycle-phosphor esters [J].
Abdou, Wafaa M. ;
Khidre, Maha D. ;
Kamel, Azza A. ;
Awad, Ghada E. A. .
MONATSHEFTE FUR CHEMIE, 2014, 145 (04) :675-682
[2]   Novel 5-Ethoxy-5H-5λ5-[1,2,4]triazolo[5,1-e][1,4,2]diazaphosphol-5-ones: One-Pot Synthesis, Characterization, and Antimicrobial Activities [J].
Ali, T. E. ;
Assiri, M. A. .
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2022, 58 (01) :94-98
[3]   SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME NEW PHOSPHORUS COMPOUNDS CONTAINING PYRANOPYRAZOLE MOIETY [J].
Ali, Tarik E. ;
Assiri, Mohammed A. ;
El-Shaaer, Hafez M. ;
Abed-Kariem, Somaia M. ;
Abdel-Monem, Wafaa R. ;
EL-Edfawy, Somaya M. ;
Hassanin, Noha M. ;
Shati, Ali A. ;
Alfaifi, Mohammad Y. ;
Elbehairi, Serag Eldin, I .
HETEROCYCLES, 2021, 102 (06) :1119-1137
[4]   One-pot synthesis and antimicrobial of novel 6-ethoxy-6-oxido-3-oxo(thioxo) (imino)-5-substituted-2,7-dihydro-1,2,4-triazolo[3,4-e][1,2,3]diazaphospholes [J].
Ali, Tarik E. ;
Assiri, Mohammed A. .
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2021, 196 (11) :965-969
[5]   FIRST SYNTHESIS OF BENZO [e] [1,3,2]DIAZAPHOSPHININO[1,6-c]-[1,3,2]OXAZAPHOSPHININES [J].
Ali, Tarik E. ;
Assiri, Mohammed A. ;
Yahia, Ibrahim S. .
HETEROCYCLES, 2019, 98 (09) :1265-1272
[6]   REACTION OF 2-IMINO-2H-CHROMENE-3-CARBOXAMIDE WITH PHOSPHORUS HALIDES: SYNTHESIS OF SOME NOVEL CHROMENO[2,3-d][1,3,2]DIAZAPHOSPHININES AND CHROMENO[4,3-c][1,2]-AZAPHOSPHOLE AND THEIR ANTIOXIDANT AND CYTOTOXICITY PROPERTIES [J].
Ali, Tarik E. ;
Assiri, Mohammed A. ;
El-Shaaer, Hafez M. ;
Fouda, Ahmed M. ;
Hassan, Mohamed M. ;
Hassanin, Noha M. .
HETEROCYCLES, 2019, 98 (05) :681-692
[7]   A Convenient Synthetic Route of Diethyl (4-Oxo-chromeno[2,3-d]pyrimidin-2(5)-yl)phosphonates [J].
Ali, Tarik E. ;
Assiri, Mohammed A. ;
Hassanin, Noha M. ;
Yahia, I. S. ;
Hussien, Mai S. A. .
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 56 (05) :1684-1686
[8]   FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF NOVEL 8-METHYL-9-SUBSTITUTED-2,10-DIARYL-2,3-DIHYDRO-10H-PYRANO [3,2-e][1,2,4,3] TRIAZAPHOSPHOLO[1,5-c]PYRIMIDINE [J].
Bakhotmah, Dina A. ;
Ali, Tank E. .
HETEROCYCLES, 2020, 100 (11) :1914-1919
[9]   New anellated 4H-1,4,2-diazaphospholes [J].
Betzl, Wolfgang ;
Hettstedt, Christina ;
Karaghiosoff, Konstantin .
NEW JOURNAL OF CHEMISTRY, 2013, 37 (02) :481-487
[10]  
Boechat N., 2014, ORGANIC COMPOUNDS CO
123