Factors affecting early childhood growth in hypoxic-ischemic encephalopathy treated with hypothermia

被引:2
|
作者
Jayakumar, Srishti [1 ,2 ]
Burton, Vera Joanna [1 ,2 ]
Perin, Jamie [3 ]
Asafu-Adjaye, Daniella [1 ,2 ]
Cristofalo, Elizabeth [4 ]
Northington, Frances [1 ,2 ]
Chavez-Valdez, Raul [1 ,2 ]
Leppert, Mary [1 ,2 ]
Allen, Marilee [1 ,2 ]
Gerner, Gwendolyn [1 ,2 ]
机构
[1] Kennedy Krieger Inst, Dept Neurol & Dev Med, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Dept Pediat, Div Neonatol, Neurosci Intens Care Nursery,Sch Med, Baltimore, MD 21205 USA
[3] Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA
[4] Frederick Mem Hosp, Dept Neonatol, Frederick, MD USA
关键词
THERAPEUTIC HYPOTHERMIA; INJURY; OUTCOMES; INFANTS;
D O I
10.1038/s41372-024-01890-x
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
INTRODUCTION: There is an extensive body of research regarding neurological outcomes following neonatal hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH), with limited data on growth outcomes. We examined perinatal characteristics associated with postnatal growth in this population. METHODS: Convenience cohort of 66 infants with HIE who underwent TH and participated in follow-up at 24 months of age were included. Regression modeling including perinatal anthropomorphics, markers of HIE, and systemic injury was used to evaluate growth at 24 months. RESULTS: Birth head circumference was associated with weight (p = 0.036). MRI severity, pH at admission and birth head circumference were associated with height (p = 0.043, p = 0.015 and p = 0.043 respectively). MRI severity and length of intubation were associated with head circumference (p = 0.038 and p < 0.001 respectively). CONCLUSION: There was a significant association between specific early factors and growth at 24 months among infants with HIE treated with TH.
引用
收藏
页码:532 / 538
页数:7
相关论文
共 50 条
  • [1] Risk Factors for Clinical Seizures in Neonates with Hypoxic-ischemic Encephalopathy Treated with Therapeutic Hypothermia
    Bor, Meltem
    Ilhan, Ozkan
    Karaca, Meryem
    Calik, Mustafa
    KLINISCHE PADIATRIE, 2022, 234 (04): : 206 - 214
  • [2] Therapeutic Hypothermia in Neonatal Hypoxic-Ischemic Encephalopathy
    Wassink, Guido
    Davidson, Joanne O.
    Dhillon, Simerdeep K.
    Zhou, Kelly
    Bennet, Laura
    Thoresen, Marianne
    Gunn, Alistair J.
    CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2019, 19 (02)
  • [3] Individualized Neuroprognostication in Neonates With Hypoxic-Ischemic Encephalopathy Treated With Hypothermia
    Van Steenis, Andrea
    Cizmeci, Mehmet N.
    Groenendaal, Floris
    Thoresen, Marianne
    Cowan, Frances M.
    de Vries, Linda S.
    Steggerda, Sylke J.
    NEUROLOGY-CLINICAL PRACTICE, 2025, 15 (01)
  • [4] Biomarkers in newborns with hypoxic-ischemic encephalopathy treated with therapeutic hypothermia
    Michniewicz, Barbara
    Szpecht, Dawid
    Sowinska, Anna
    Sibiak, Rafal
    Szymankiewicz, Marta
    Gadzinowski, Janusz
    CHILDS NERVOUS SYSTEM, 2020, 36 (12) : 2981 - 2988
  • [5] Neonatal Hypoxic-Ischemic Encephalopathy and Hypothermia Treatment
    Arnautovic, Tamara
    Sinha, Sanghamitra
    Laptook, Abbot R.
    OBSTETRICS AND GYNECOLOGY, 2024, 143 (01) : 67 - 81
  • [6] Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy
    Herrera, Tamara, I
    Edwards, Laura
    Malcolm, William F.
    Smith, P. Brian
    Fisher, Kimberley A.
    Pizoli, Carolyn
    Gustafson, Kathryn E.
    Goldstein, Ricki F.
    Cotten, C. Michael
    Goldberg, Ronald N.
    Bidegain, Margarita
    EARLY HUMAN DEVELOPMENT, 2018, 125 : 1 - 7
  • [7] Therapeutic Hypothermia in Hypoxic-Ischemic Encephalopathy
    B. Vishnu Bhat
    B. Adhisivam
    The Indian Journal of Pediatrics, 2015, 82 : 105 - 106
  • [8] Hypothermia for newborns with hypoxic-ischemic encephalopathy
    Lemyre, Brigitte
    Chau, Vann
    PAEDIATRICS & CHILD HEALTH, 2018, 23 (04) : 285 - 291
  • [9] Outcomes in childhood following therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy (HIE)
    Natarajan, Girija
    Pappas, Athina
    Shankaran, Seetha
    SEMINARS IN PERINATOLOGY, 2016, 40 (08) : 549 - 555
  • [10] A Case of an Infant with Hydrops Fetalis and Hypoxic-Ischemic Encephalopathy Treated with Therapeutic Hypothermia
    Stockley, Elizabeth
    Gowda, Harsha
    THERAPEUTIC HYPOTHERMIA AND TEMPERATURE MANAGEMENT, 2022, 12 (01) : 43 - 46