Synthesis of Fluoren-9-ones via Pd-Catalyzed Annulation of 2-Iodobiphenyls with Vinylene Carbonate

被引：3

作者：

Li, Wenguang ^{[1
,2
]}

Yu, Yongqi ^{[1
]}

Yang, Jie ^{[1
]}

Fu, Kaifang ^{[1
]}

Zhang, Xu ^{[1
]}

Shi, Shukui ^{[1
]}

Li, Ting ^{[1
]}

机构：

[1] Nanyang Normal Univ, Coll Chem & Pharmaceut Engn, Drug Synth Engn Technol Res Ctr Henan Prov Photoel, Engn Technol Res Ctr Henan Prov Solar Catalysis, Nanyang 473061, Henan, Peoples R China

[2] Henan Tianguan Enterprise Grp Co Ltd, State Key Lab Motor Vehicle Biofuel Technol, Nanyang 473000, Henan, Peoples R China

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2024年 / 19卷 / 04期

关键词：

C-H activation; palladium catalysis; vinylene carbonate; carbon monoxide transfer; versatile synthon; C-H ACTIVATION; ONE-POT SYNTHESIS; BOND ACTIVATION; BUILDING-BLOCKS; ARYL HALIDES; FLUORENONES; DERIVATIVES; ARYLATION; TILORONE; ROUTE;

D O I：

10.1002/asia.202301040

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium-catalyzed reaction for intermolecular selective C-H cyclocarbonylation of 2-iodobiphenyls is described. Intriguingly, the vinylene carbonate acts as a carbon monoxide transfer agent to enable the annulation reaction. Moreover, as a versatile synthon, fluoren-9-one can be transformed into a variety of functionalized organic molecules, such as [1,1'-biphenyl]-2-carboxylic acid, 1'H,3'H-spiro[fluorene-9,2'-perimidine] and N-tosylhydrazones.

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页数：6

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