Synthesis of Fluoren-9-ones via Pd-Catalyzed Annulation of 2-Iodobiphenyls with Vinylene Carbonate

被引：3
作者：
Li, Wenguang [1 ,2 ]
Yu, Yongqi [1 ]
Yang, Jie [1 ]
Fu, Kaifang [1 ]
Zhang, Xu [1 ]
Shi, Shukui [1 ]
Li, Ting [1 ]
机构：
[1] Nanyang Normal Univ, Coll Chem & Pharmaceut Engn, Drug Synth Engn Technol Res Ctr Henan Prov Photoel, Engn Technol Res Ctr Henan Prov Solar Catalysis, Nanyang 473061, Henan, Peoples R China
[2] Henan Tianguan Enterprise Grp Co Ltd, State Key Lab Motor Vehicle Biofuel Technol, Nanyang 473000, Henan, Peoples R China
来源：
CHEMISTRY-AN ASIAN JOURNAL | 2024年 / 19卷 / 04期
关键词：
C-H activation; palladium catalysis; vinylene carbonate; carbon monoxide transfer; versatile synthon; C-H ACTIVATION; ONE-POT SYNTHESIS; BOND ACTIVATION; BUILDING-BLOCKS; ARYL HALIDES; FLUORENONES; DERIVATIVES; ARYLATION; TILORONE; ROUTE;
D O I：
10.1002/asia.202301040
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A palladium-catalyzed reaction for intermolecular selective C-H cyclocarbonylation of 2-iodobiphenyls is described. Intriguingly, the vinylene carbonate acts as a carbon monoxide transfer agent to enable the annulation reaction. Moreover, as a versatile synthon, fluoren-9-one can be transformed into a variety of functionalized organic molecules, such as [1,1'-biphenyl]-2-carboxylic acid, 1'H,3'H-spiro[fluorene-9,2'-perimidine] and N-tosylhydrazones.
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页数：6
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