Transbronchial lung cryobiopsy in interstitial lung diseases

被引:1
作者
Menigoz, C. [1 ]
Dirou, S. [1 ]
Sagan, C. [2 ]
Corne, F. [1 ,5 ]
Moui, A. [1 ]
Defrance, C. [3 ]
Liberge, R. [3 ]
Morla, O. [3 ]
Patarin, V. [3 ]
Nicolas, A. [3 ]
Kandel-Aznar, C. [2 ]
Lacoste, P. [4 ]
Clarke, J. P. [1 ,6 ]
Cavailles, A. [1 ]
Cellerin, L. [1 ]
Blanc, F. -X. [1 ]
机构
[1] Nantes Univ, Inst Thorax, Serv Pneumol, CHU Nantes, Nantes, France
[2] Nantes Univ, Serv Anatomopathol, CHU Nantes, Nantes, France
[3] Nantes Univ, Serv Imagerie Med, CHU Nantes, Nantes, France
[4] Nantes Univ, Inst Thorax, Serv Chirurg Thorac & Cardiovasc, CHU Nantes, Nantes, France
[5] Clin Jules Verne, Consultat Pneumol, Nantes, France
[6] Clin ELSAN Sante Atlantique, Consultat Pneumol, St Herblain, France
关键词
Bronchoscopy; Interstitial lung diseases; Histology; Idiopathic pulmonary fibrosis; Clinical pathology; IDIOPATHIC PULMONARY-FIBROSIS; DIAGNOSTIC YIELD; BIOPSY; SAFETY; STANDARDIZATION; CRYOTHERAPY; INCREASES; UTILITY;
D O I
10.1016/j.rmr.2023.04.003
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
In some cases of interstitial lung disease (ILD), clinical and biological findings associated with CT scan pattern during multidisciplinary discussion (MDD) fail to yield a confident diagnosis. In these cases, histology may be necessary. Transbronchial lung cryobiopsy (TBLC) is a bronchoscopic procedure that has been developed in recent years and currently contributes to diagnostic work-up in patients with ILD. TBLC provides tissue samples for histological analysis with an acceptable risk of complications, consisting mainly in pneumothorax or bleeding. In addition to higher diagnostic yield than conventional forceps biopsies, the procedure shows a better safety profile than surgical biopsies. The indication to perform TBLC is decided during a 1st MDD and during a 2nd MDD, results can provide a diagnostic yield approximating 80%. TBLC appears to be an attractive, minimally invasive technique to be proposed as a first-line procedure in selected patients in experienced centers, while surgical lung biopsy may be considered as a second-line solution. & COPY; 2023 SPLF. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:469 / 478
页数:10
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