Tumor budding in gastric cancer

被引：2

作者：

Xiao, Shuo-Meng ^{[1
]}

Li, Jian ^{[2
]}

机构：

[1] Sichuan Canc Hosp, Dept Gastr Surg, Chengdu 610041, Sichuan, Peoples R China

[2] Third Hosp Mianyang, Sichuan Mental Hlth Ctr, Dept Gen Surg, 190 East Sect Jiannan Rd, Mianyang 621000, Sichuan, Peoples R China

来源：

WORLD JOURNAL OF GASTROINTESTINAL SURGERY | 2023年 / 15卷 / 04期

关键词：

Tumor budding; Gastric cancer; Poorly differentiated cluster; Prognosis; Lymph node metastasis; PROGNOSTIC-SIGNIFICANCE; COLORECTAL-CANCER; INVASIVE FRONT; CELL INVASION; CARCINOMA; IMPACT; PARAMETER; CRITERIA;

D O I：

10.4240/wjgs.v15.i4.578

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The tumor, nodes, metastasis (TNM) staging system has long been the gold standard for the classification and prognosis of solid tumors. However, the TNM staging system is not without limitations. Prognostic heterogeneity exists within patients at the same stage. Therefore, the pursuit of other biomarkers with the potential to classify patients with cancer has never stopped. One of them, tumor budding (TB), has gained much success in colorectal cancer. In recent years, TB in gastric cancer has attracted much attention from researchers, beginning to reveal the molecular and biological aspects of this phenomenon in gastric cancer, and has emerged as a promising prognostic biomarker in gastric cancer, predicting disease progression and unfavorable survival. Therefore, it is time and essential to provide a holistic overview of TB in gastric cancer, which has not been achieved and is the aim of this review.

引用

页码：578 / 591

页数：14

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