Urinary Continence Recovery after Robotic Radical Prostatectomy without Anterior or Posterior Reconstruction: Experience from a Tertiary Referral Center

被引:7
|
作者
Sessa, Francesco [1 ,2 ]
Nicoletti, Rossella [1 ]
Pecoraro, Alessio [1 ]
Polverino, Paolo [1 ]
Rivetti, Anna [1 ,2 ]
Conte, Francesco Lupo [1 ]
Lo Re, Mattia [1 ]
Belmonte, Mario [1 ]
Alberti, Andrea [1 ]
Dibilio, Edoardo [1 ]
Gallo, Maria Lucia [1 ]
Manera, Alekseja [1 ]
Gacci, Mauro [1 ,2 ]
Sebastianelli, Arcangelo [1 ]
Vignolini, Graziano [1 ]
Serni, Sergio [1 ,2 ]
Campi, Riccardo [1 ,2 ]
Li Marzi, Vincenzo [1 ]
机构
[1] Univ Florence, Careggi Hosp, Unit Urol Robot Surg & Renal Transplantat, I-50100 Florence, Italy
[2] Univ Florence, Dept Expt & Clin Med, I-50100 Florence, Italy
关键词
continence; post-prostatectomy incontinence; RALP; radical prostatectomy; prostate cancer; FUNCTIONAL OUTCOMES; PRESERVATION; INCONTINENCE; BLADDER; CLASSIFICATION; METAANALYSIS; ANASTOMOSIS; SINGLE;
D O I
10.3390/jcm12041358
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: The aim of our study is to evaluate the prevalence and predictive factors of short- (30 d) and mid-term continence in a contemporary cohort of patients treated with robotic-assisted laparoscopic prostatectomy (RALP) without any posterior or anterior reconstruction at our referral academic center. Methods: Data from patients undergoing RALP between January 2017 and March 2021 were prospectively collected. RALP was performed by three highly experienced surgeons following the principles of the Montsouris technique, with a bladder-neck-sparing intent and maximal preservation of the membranous urethra (if oncologically safe) without any anterior/posterior reconstruction. (Self-assessed urinary incontinence (UI) was defined as the need of one or more pads per die (excluding the need for a safety pad/die. Univariable and multivariable logistic regression analysis was used to assess the independent predictors of early incontinence among routinely collected patient- and tumor-related variables). Results: A total of 925 patients were included; of these, 353 underwent RALP (38.2%) without nerve-sparing intent. The median patient age and BMI were 68 years (IQR 63-72) and 26 (IQR 24.0-28.0), respectively. Overall, 159 patients (17.2%) reported early (30 d) incontinence. In multivariable analysis adjusting for patient- and tumor-related features, a non-nerve-sparing procedure (OR: 1.57 [95% CI: 1.03-2.59], p = 0.035) was independently associated with the risk of urinary incontinence in the short-term period, while the absence of cardiovascular diseases before surgery (OR: 0.46 [95% CI: 0.320.67], p <= 0.01) was a protective factor for this outcome. At a median follow-up of 17 months (IQR 10-24), 94.5% of patients reported to be continent. Conclusions: In experienced hands, most patients fully recover urinary continence after RALP at mid-term follow-up. On the contrary, the proportion of patients who reported early incontinence in our series was modest but not negligible. The implementation of surgical techniques advocating anterior and/or posterior fascial reconstruction might improve the early continence rate in candidates for RALP.
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页数:14
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