Electrospun Nanofiber Scaffolds Loaded with Metal-Based Nanoparticles for Wound Healing

被引:7
作者
Dang, Zheng [1 ]
Ma, Xuemei [1 ]
Yang, Zihao [1 ]
Wen, Xiaohu [1 ]
Zhao, Pengxiang [1 ]
机构
[1] Beijing Univ Technol, Fac Environm & Life, Beijing 100124, Peoples R China
关键词
electrospinning; nanofiber scaffolds; extracellular matrix; metal-based nanoparticles; nanostructure; wound healing; SILVER NANOPARTICLES; GOLD NANOPARTICLES; EXTRACELLULAR-MATRIX; ANTIINFLAMMATORY EFFICACY; POTENTIAL ANTIBACTERIAL; BIOMEDICAL APPLICATIONS; COPPER NANOPARTICLES; OXIDE NANOPARTICLES; GREEN SYNTHESIS; IN-VITRO;
D O I
10.3390/polym16010024
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Failures of wound healing have been a focus of research worldwide. With the continuous development of materials science, electrospun nanofiber scaffolds loaded with metal-based nanoparticles provide new ideas and methods for research into new tissue engineering materials due to their excellent antibacterial, anti-inflammatory, and wound healing abilities. In this review, the stages of extracellular matrix and wound healing, electrospun nanofiber scaffolds, metal-based nanoparticles, and metal-based nanoparticles supported by electrospun nanofiber scaffolds are reviewed, and their characteristics and applications are introduced. We discuss in detail the current research on wound healing of metal-based nanoparticles and electrospun nanofiber scaffolds loaded with metal-based nanoparticles, and we highlight the potential mechanisms and promising applications of these scaffolds for promoting wound healing.
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页数:21
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