Additive-free synthesis of S-substituted isothioureas via visible-light-induced four-component reaction of α-diazoesters, aryl isothiocyanates, amines and cyclic ethers

被引：53

作者：

Lv, Yufen ^{[1
]}

Ding, Hongyu ^{[1
]}

You, Jinmao ^{[1
,2
]}

Wei, Wei ^{[1
]}

Yi, Dong ^{[3
]}

机构：

[1] Qufu Normal Univ, Key Lab Catalyt Convers & Clean Energy Univ Shando, Sch Chem & Chem Engn, Qufu 273165, Peoples R China

[2] Shaoxing Univ, Coll Chem & Chem Engn, Shaoxing 312000, Peoples R China

[3] Southwest Med Univ, Sch Pharm, Luzhou 646000, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2024年 / 35卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Visible-light; Additive-free; Four-component reaction; S -Substituted isothioureas; DERIVATIVES; ARYLATION; GUANIDINES; IODIDES; ALKENES;

D O I：

10.1016/j.cclet.2023.109107

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An additive-free and environmentally friendly strategy has been realized for the construction of S-substituted isothioureas through visible-light-induced multicomponent reaction starting from alpha- diazoesters, aryl isothiocyanates, amines and cyclic ethers. This methodology features simple operation, mild reaction conditions, favorable functional group tolerance, easily available starting materials and high efficiency.(c) 2023 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.

引用

页数：5

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