Evolutionary Dynamics and Intermittent Therapy for Metastatic Cancers

被引:6
作者
Chahoud, Jad [1 ]
Anderson, Alexander R. A. [2 ]
Zhang, Jingsong [1 ]
Brown, Joel [2 ]
Gatenby, Robert A. [2 ,3 ,4 ]
机构
[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Genitourinary Oncol, Tampa, FL USA
[2] H Lee Moffitt Canc Ctr & Res Inst, Dept Integrated Math Oncol, Tampa, FL USA
[3] H Lee Moffitt Canc Ctr & Res Inst, Dept Radiol, Dept Integrated Math Oncol, Tampa, FL USA
[4] H Lee Moffitt Canc Ctr & Res Inst, 3011 Holly Dr, Tampa, FL 33612 USA
关键词
MELANOMA; BRAF;
D O I
10.1200/JCO.23.00647
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:4469 / +
页数:4
相关论文
共 19 条
[1]   Continuous versus intermittent BRAF and MEK inhibition in patients withBRAF-mutated melanoma: a randomized phase 2 trial [J].
Algazi, Alain P. ;
Othus, Megan ;
Daud, Adil, I ;
Lo, Roger S. ;
Mehnert, Janice M. ;
Thach-Giao Truong ;
Conry, Robert ;
Kendra, Kari ;
Doolittle, Gary C. ;
Clark, Joseph, I ;
Messino, Michael J. ;
Moore, Dennis F., Jr. ;
Lao, Christopher ;
Faller, Bryan A. ;
Govindarajan, Rangaswamy ;
Harker-Murray, Amy ;
Dreisbach, Luke ;
Moon, James ;
Grossmann, Kenneth F. ;
Ribas, Antoni .
NATURE MEDICINE, 2020, 26 (10) :1564-+
[2]   Exploiting ecological principles to better understand cancer progression and treatment [J].
Basanta, David ;
Anderson, Alexander R. A. .
INTERFACE FOCUS, 2013, 3 (04)
[3]   Predicting patient-specific response to adaptive therapy in metastatic castration-resistant prostate cancer using prostate-specific antigen dynamics [J].
Brady-Nicholls, Renee ;
Zhang, Jingsong ;
Zhang, Tian ;
Wang, Andrew Z. ;
Butler, Robert ;
Gatenby, Robert A. ;
Enderling, Heiko .
NEOPLASIA, 2021, 23 (09) :851-858
[4]   Temporary treatment cessation versus continuation of first-line tyrosine kinase inhibitor in patients with advanced clear cell renal cell carcinoma (STAR): an open-label, non-inferiority, randomised, controlled, phase 2/3 trial [J].
Brown, Janet E. ;
Royle, Kara-Louise ;
Gregory, Walter ;
Ralph, Christy ;
Maraveyas, Anthony ;
Din, Omar ;
Eisen, Timothy ;
Nathan, Paul ;
Powles, Tom ;
Griffiths, Richard ;
Jones, Robert ;
Vasudev, Naveen ;
Wheater, Matthew ;
Hamid, Abdel ;
Waddell, Tom ;
McMenemin, Rhona ;
Patel, Poulam ;
Larkin, James ;
Faust, Guy ;
Martin, Adam ;
Swain, Jayne ;
Bestall, Janine ;
McCabe, Christopher ;
Meads, David ;
Goh, Vicky ;
Wah, Tze Min ;
Brown, Julia ;
Hewison, Jenny ;
Selby, Peter ;
Collinson, Fiona .
LANCET ONCOLOGY, 2023, 24 (03) :213-227
[5]   Optimal control to reach eco-evolutionary stability in metastatic castrate-resistant prostate cancer [J].
Cunningham, Jessica ;
Thuijsman, Frank ;
Peeters, Ralf ;
Viossat, Yannick ;
Brown, Joel ;
Gatenby, Robert ;
Stankova, Katerina .
PLOS ONE, 2020, 15 (12)
[6]   Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer [J].
Cunningham, Jessica J. ;
Brown, Joel S. ;
Gatenby, Robert A. ;
Stankova, Katerina .
JOURNAL OF THEORETICAL BIOLOGY, 2018, 459 :67-78
[7]   Intermittent dosing with vemurafenib in BRAF V600E-mutant melanoma: review of a case series [J].
Dooley, Andrew J. ;
Gupta, Avinash ;
Bhattacharyya, Madhumita ;
Middleton, Mark R. .
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2014, 6 (06) :262-266
[8]   Integrating evolutionary dynamics into cancer therapy [J].
Gatenby, Robert A. ;
Brown, Joel S. .
NATURE REVIEWS CLINICAL ONCOLOGY, 2020, 17 (11) :675-686
[9]   Eradicating Metastatic Cancer and the Eco-Evolutionary Dynamics of Anthropocene Extinctions [J].
Gatenby, Robert A. ;
Artzy-Randrup, Yael ;
Epstein, Tamir ;
Reed, Damon R. ;
Brown, Joel S. .
CANCER RESEARCH, 2020, 80 (03) :613-623
[10]   Adaptive Therapy [J].
Gatenby, Robert A. ;
Silva, Ariosto S. ;
Gillies, Robert J. ;
Frieden, B. Roy .
CANCER RESEARCH, 2009, 69 (11) :4894-4903