Nanotechnology: A promising strategy for the control of parasitic infections

被引:10
|
作者
AlGabbani, Qwait [1 ]
机构
[1] Prince Sattam Bin Abdulaziz Univ, Coll Sci & Humanities, Dept Biol, Al Kharj, Saudi Arabia
关键词
Parasitic infections; Nanoparticles; Mechanism; Therapeutic agents; Strategy; SILVER NANOPARTICLES; DRUG-RESISTANCE; GOLD NANOPARTICLES; GREEN SYNTHESIS; TOXOPLASMA-GONDII; DELIVERY-SYSTEMS; LEISHMANIASIS; CHITOSAN;
D O I
10.1016/j.exppara.2023.108548
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Annually 3.5 billion people are affected by the parasitic infections that results around 200,000 deaths per annum. Major diseases occur due to the neglected tropical parasites. Variety of methods have been used to treat the parasitic infections but now these methods have become ineffective due to the development of resistance in the parasites and some other side effects of traditional treatment methods. Previous methods include use of chemotherapeutic agents and ethnobotanicals for the treatment of parasites. Parasites have developed resistance against the chemotherapeutic agents. A major problem related to Ethnobotanicals is the unequal availability of drug at the target site which is responsible for the low efficacy of drug. Nanotechnology technology involves the manipulation of matter on a nanoscale level and has the potential to enhance the efficacy and safety of existing drugs, develop new treatments, and improve diagnostic methods for parasitic infections. Nanoparticles can be designed to selectively target parasites while minimizing toxicity to the host, and they can also be used to improve drug delivery and increase drug stability. Some important nanotechnology-based tools for parasitic control include nanoparticle-based drug delivery, nanoparticle diagnostics, nanoparticle vaccines, nanoparticle insecticides. Nanotechnology has the potential to revolutionize the field of parasitic control by providing new methods for detection, prevention and treatment of parasitic infections. This review discusses the current state of nanotechnology-based approaches for controlling parasitic infections and highlights their potential to revolutionize the field of parasitology.
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页数:8
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