Nanotechnology: A promising strategy for the control of parasitic infections
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作者:
AlGabbani, Qwait
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Prince Sattam Bin Abdulaziz Univ, Coll Sci & Humanities, Dept Biol, Al Kharj, Saudi ArabiaPrince Sattam Bin Abdulaziz Univ, Coll Sci & Humanities, Dept Biol, Al Kharj, Saudi Arabia
AlGabbani, Qwait
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机构:
[1] Prince Sattam Bin Abdulaziz Univ, Coll Sci & Humanities, Dept Biol, Al Kharj, Saudi Arabia
Annually 3.5 billion people are affected by the parasitic infections that results around 200,000 deaths per annum. Major diseases occur due to the neglected tropical parasites. Variety of methods have been used to treat the parasitic infections but now these methods have become ineffective due to the development of resistance in the parasites and some other side effects of traditional treatment methods. Previous methods include use of chemotherapeutic agents and ethnobotanicals for the treatment of parasites. Parasites have developed resistance against the chemotherapeutic agents. A major problem related to Ethnobotanicals is the unequal availability of drug at the target site which is responsible for the low efficacy of drug. Nanotechnology technology involves the manipulation of matter on a nanoscale level and has the potential to enhance the efficacy and safety of existing drugs, develop new treatments, and improve diagnostic methods for parasitic infections. Nanoparticles can be designed to selectively target parasites while minimizing toxicity to the host, and they can also be used to improve drug delivery and increase drug stability. Some important nanotechnology-based tools for parasitic control include nanoparticle-based drug delivery, nanoparticle diagnostics, nanoparticle vaccines, nanoparticle insecticides. Nanotechnology has the potential to revolutionize the field of parasitic control by providing new methods for detection, prevention and treatment of parasitic infections. This review discusses the current state of nanotechnology-based approaches for controlling parasitic infections and highlights their potential to revolutionize the field of parasitology.
机构:
Univ Sci & Technol Meghalaya USTM, Sch Biol Sci, Dept Appl Biol, Techno City, Meghalaya, India
Kasetsart Univ, Fac Sci, Dept Phys, Bangkok, ThailandUniv Sci & Technol Meghalaya USTM, Sch Biol Sci, Dept Appl Biol, Techno City, Meghalaya, India
Ahmed, Ramzan
Mishra, Bibhudutta
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All India Inst Med Sci, Dept Gastroenterol, New Delhi, India
All India Inst Med Sci, HNU, New Delhi, IndiaUniv Sci & Technol Meghalaya USTM, Sch Biol Sci, Dept Appl Biol, Techno City, Meghalaya, India
Mishra, Bibhudutta
Mohanta, Tapan Kumar
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Univ Nizwa, Nat & Med Sci Res Ctr, Nizwa, OmanUniv Sci & Technol Meghalaya USTM, Sch Biol Sci, Dept Appl Biol, Techno City, Meghalaya, India
Mohanta, Tapan Kumar
Saravanan, Muthupandian
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Saveetha Inst Med & Tech Sci SIMATS, Saveetha Dent Coll, Dept Pharmacol, AMR & Nanotherapeut Lab, Chennai, Manipur, IndiaUniv Sci & Technol Meghalaya USTM, Sch Biol Sci, Dept Appl Biol, Techno City, Meghalaya, India
机构:
Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USA
Johns Hopkins Inst NanoBioTechnol INBT, Baltimore, MD USAMassachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USA
Chakravarthy, Krishnan V.
Boehm, Frank J.
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NanoApps Med Inc, Vancouver, BC, CanadaMassachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USA
Boehm, Frank J.
Christo, Paul J.
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Johns Hopkins Univ Hosp, Dept Anesthesiol & Crit Care Med, Div Pain Med, Baltimore, MD USAMassachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USA
机构:
Stanford Univ, Sch Med, Dept Orthopaed Surg & Bioengn, Stanford, CA 94305 USAStanford Univ, Sch Med, Dept Orthopaed Surg & Bioengn, Stanford, CA 94305 USA
Indelli, Pier Francesco
Ghirardelli, Stefano
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Stanford Univ, Sch Med, Dept Orthopaed Surg & Bioengn, Stanford, CA 94305 USAStanford Univ, Sch Med, Dept Orthopaed Surg & Bioengn, Stanford, CA 94305 USA
Ghirardelli, Stefano
Iannotti, Ferdinando
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Sapienza Univ Rome, Dept Surg & Med Sci & Translat Med, I-00185 Rome, ItalyStanford Univ, Sch Med, Dept Orthopaed Surg & Bioengn, Stanford, CA 94305 USA
Iannotti, Ferdinando
Indelli, Alessia Maria
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Stanford Univ, Sch Med, Dept Orthopaed Surg & Bioengn, Stanford, CA 94305 USAStanford Univ, Sch Med, Dept Orthopaed Surg & Bioengn, Stanford, CA 94305 USA
Indelli, Alessia Maria
Pipino, Gennaro
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Univ Vita Salute San Raffaele, Div Orthopaed Surg, I-20132 Milan, ItalyStanford Univ, Sch Med, Dept Orthopaed Surg & Bioengn, Stanford, CA 94305 USA